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Q41770644-98E9A299-25D7-4FA3-86B0-7B1820598900
Q41770644-98E9A299-25D7-4FA3-86B0-7B1820598900
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http://www.wikidata.org/entity/statement/Q41770644-98E9A299-25D7-4FA3-86B0-7B1820598900
Destabilization of akt promotes the death of myeloma cell lines.
P2860
Q41770644-98E9A299-25D7-4FA3-86B0-7B1820598900
BestRank
Statement
http://www.wikidata.org/entity/statement/Q41770644-98E9A299-25D7-4FA3-86B0-7B1820598900
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wasDerivedFrom
224a6b1f7d054f4c9628874166a11f3addeb53d9
P2860
The E3 ubiquitin ligases β-TrCP and FBXW7 cooperatively mediates GSK3-dependent Mcl-1 degradation induced by the Akt inhibitor API-1, resulting in apoptosis.