FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells
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Functional association between SLAP-130 and SLP-76 in Jurkat T cellsFyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeletonRegulation and function of SKAP-55 non-canonical motif binding to the SH3c domain of adhesion and degranulation-promoting adaptor proteinPRAM-1 is required for optimal integrin-dependent neutrophil functionB cell adaptor containing src homology 2 domain (BASH) links B cell receptor signaling to the activation of hematopoietic progenitor kinase 1SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55The Fyn-ADAP Axis: Cytotoxicity Versus Cytokine Production in Killer CellsNovel isoform of lymphoid adaptor FYN-T-binding protein (FYB-130) interacts with SLP-76 and up-regulates interleukin 2 productionHematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytesDeficiency of ADAP/Fyb/SLAP-130 destabilizes SKAP55 in Jurkat T cellsPhysical and functional association of c-Src and adhesion and degranulation promoting adaptor protein (ADAP) in osteoclastogenesis in vitroHematopoietic adaptors in T-cell signaling: potential applications to transplantationADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugationARAP, a Novel Adaptor Protein, Is Required for TCR Signaling and Integrin-Mediated AdhesionThe N terminus of SKAP55 enables T cell adhesion to TCR and integrin ligands via distinct mechanisms.ADAP is required for normal alphaIIbbeta3 activation by VWF/GP Ib-IX-V and other agonists.Adaptor FYB (Fyn-binding protein) regulates integrin-mediated adhesion and mediator release: differential involvement of the FYB SH3 domainRecruitment of dynein to the Jurkat immunological synapseSLP-76-ADAP adaptor module regulates LFA-1 mediated costimulation and T cell motility.SH2 domain containing leukocyte phosphoprotein of 76-kDa (SLP-76) feedback regulation of ZAP-70 microclustering.Completion of proteomic data sets by Kd measurement using cell-free synthesis of site-specifically labeled proteins.The molecular adapter SLP-76 relays signals from platelet integrin alphaIIbbeta3 to the actin cytoskeleton.Signal transduction by different forms of the γδ T cell-specific pattern recognition receptor WC1.Receptor-stimulated oxidation of SHP-2 promotes T-cell adhesion through SLP-76-ADAPSignalling scaffolds and adaptors in T-cell immunity.ADAP-ting TCR signaling to integrins.T-cell receptor signaling to integrins.Genetic analysis of integrin activation in T lymphocytes.The pleckstrin homology domain in the SKAP55 adapter protein defines the ability of the adapter protein ADAP to regulate integrin function and NF-kappaB activation.The TCR ADAPts to integrin-mediated cell adhesion.Positive and negative adaptors in T-cell signalling.Crucial role of SLP-76 and ADAP for neutrophil recruitment in mouse kidney ischemia-reperfusion injury.Analysis of Phosphorylation-dependent Protein Interactions of Adhesion and Degranulation Promoting Adaptor Protein (ADAP) Reveals Novel Interaction Partners Required for Chemokine-directed T cell Migration.Recruitment of SLP-76 to the membrane and glycolipid-enriched membrane microdomains replaces the requirement for linker for activation of T cells in T cell receptor signalingRegulation of T-cell antigen receptor-mediated inside-out signaling by cytosolic adapter proteins and Rap1 effector molecules.Distinct regulation of integrin-dependent T cell conjugate formation and NF-kappa B activation by the adapter protein ADAP.SLP-76 sterile α motif (SAM) and individual H5 α helix mediate oligomer formation for microclusters and T-cell activation.SKAP-55, SKAP-55-related and ADAP adaptors modulate integrin-mediated immune-cell adhesion.T-cell receptor antagonists induce Vav phosphorylation by selective activation of Fyn kinase.T cell receptor "inside-out" pathway via signaling module SKAP1-RapL regulates T cell motility and interactions in lymph nodes
P2860
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P2860
FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
FYN-T-FYB-SLP-76 interactions ...... kin 2 transcription in T-cells
@ast
FYN-T-FYB-SLP-76 interactions ...... kin 2 transcription in T-cells
@en
FYN-T-FYB-SLP-76 interactions ...... kin 2 transcription in T-cells
@en-gb
FYN-T-FYB-SLP-76 interactions ...... kin 2 transcription in T-cells
@nl
type
label
FYN-T-FYB-SLP-76 interactions ...... kin 2 transcription in T-cells
@ast
FYN-T-FYB-SLP-76 interactions ...... kin 2 transcription in T-cells
@en
FYN-T-FYB-SLP-76 interactions ...... kin 2 transcription in T-cells
@en-gb
FYN-T-FYB-SLP-76 interactions ...... kin 2 transcription in T-cells
@nl
prefLabel
FYN-T-FYB-SLP-76 interactions ...... kin 2 transcription in T-cells
@ast
FYN-T-FYB-SLP-76 interactions ...... kin 2 transcription in T-cells
@en
FYN-T-FYB-SLP-76 interactions ...... kin 2 transcription in T-cells
@en-gb
FYN-T-FYB-SLP-76 interactions ...... kin 2 transcription in T-cells
@nl
P2093
P2860
P356
P1476
FYN-T-FYB-SLP-76 interactions ...... kin 2 transcription in T-cells
@en
P2093
P2860
P304
P356
10.1074/JBC.274.30.21170
P407
P577
1999-07-23T00:00:00Z