Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity - sprookjes - yvandenbroek - TriplyDB

Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity

Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity

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Mediator modulates Gli3-dependent Sonic hedgehog signaling Gli proteins and the control of spinal-cord patterning A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube Establishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: the role of negative feedback Sonic hedgehog signaling controls thalamic progenitor identity and nuclei specification in mice The hedgehog pathway in triple-negative breast cancer Morphogen rules: design principles of gradient-mediated embryo patterning Roles for Hedgehog signaling in adult organ homeostasis and repair Primary cilium and sonic hedgehog signaling during neural tube patterning: role of GPCRs and second messengers Shh and Gli3 regulate formation of the telencephalic-diencephalic junction and suppress an isthmus-like signaling source in the forebrain Making a grade: Sonic Hedgehog signalling and the control of neural cell fate THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse development Forward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signaling Temporal deletion of Arl13b reveals that a mispatterned neural tube corrects cell fate over time The transcriptional repressor Glis2 is a novel binding partner for p120 catenin Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube The intraflagellar transport protein IFT80 is required for cilia formation and osteogenesis A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord Specific requirements of sonic hedgehog signaling during oligodendrocyte development Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling Intraflagellar transport, cilia, and mammalian Hedgehog signaling: analysis in mouse embryonic fibroblasts EvoD/Vo: the origins of BMP signalling in the neuroectoderm Graded hedgehog and fibroblast growth factor signaling independently regulate pituitary cell fates and help establish the pars distalis and pars intermedia of the zebrafish adenohypophysis.Turning heads: development of vertebrate branchiomotor neurons.Foxj1 regulates floor plate cilia architecture and modifies the response of cells to sonic hedgehog signalling Threshold-dependent BMP-mediated repression: a model for a conserved mechanism that patterns the neuroectoderm Human GLI3 intragenic conserved non-coding sequences are tissue-specific enhancers.Point mutations in GLI3 lead to misregulation of its subcellular localization.Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb development Integration of signals along orthogonal axes of the vertebrate neural tube controls progenitor competence and increases cell diversity Sonic hedgehog signaling in the postnatal brain.Yeast-based assay identifies novel Shh/Gli target genes in vertebrate development A transcription factor network specifying inhibitory versus excitatory neurons in the dorsal spinal cord.The cellular and molecular etiology of the craniofacial defects in the avian ciliopathic mutant talpid2.A theoretical framework for the regulation of Shh morphogen-controlled gene expression The chicken talpid3 gene encodes a novel protein essential for Hedgehog signaling

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Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity

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2002 nî lūn-bûn

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2002年論文

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2002年論文

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Dorsal-ventral patterning of t ...... scriptional repressor activity

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Dorsal-ventral patterning of t ...... scriptional repressor activity

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Dorsal-ventral patterning of t ...... scriptional repressor activity

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Dorsal-ventral patterning of t ...... scriptional repressor activity

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Dorsal-ventral patterning of t ...... scriptional repressor activity

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Dorsal-ventral patterning of t ...... scriptional repressor activity

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Dorsal-ventral patterning of t ...... scriptional repressor activity

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Dorsal-ventral patterning of t ...... scriptional repressor activity

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Dorsal-ventral patterning of t ...... scriptional repressor activity

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Genes & Development

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Dorsal-ventral patterning of t ...... scriptional repressor activity

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Despina Stamataki

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Jens Böse

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Madelen Persson

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Pascal te Welscher

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Ulrich Rüther

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P2860

Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

Opponent activities of Shh and BMP signaling during floor plate induction in vivo

The GLI-Kruppel family of human genes

Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers

A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro

Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation

Gli3 is required for Emx gene expression during dorsal telencephalon development

Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3

Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling

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2865-78

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2721533

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10.1101/GAD.243402

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22

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16

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Elisabet Andersson

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2002-11-15T00:00:00Z

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11031509

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P698

12435629

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GLI-Kruppel family member GLI3

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187477

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