Mediator modulates Gli3-dependent Sonic hedgehog signaling
about
Identification of the gene transcription repressor domain of Gli3Mediator is a transducer of amyloid-precursor-protein-dependent nuclear signallingMED12 mutations link intellectual disability syndromes with dysregulated GLI3-dependent Sonic Hedgehog signalingMED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expressionMediator kinase module and human tumorigenesisContext-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapyEvolutionary change within a bipotential switch shaped the sperm/oocyte decision in hermaphroditic nematodesThe Mediator complex and transcription regulationMouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathwayA sensitized mutagenesis screen identifies Gli3 as a modifier of Sox10 neurocristopathyPoint mutations in GLI3 lead to misregulation of its subcellular localization.Mutation analysis of components of the Mediator kinase module in MED12 mutation-negative uterine leiomyomas.Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity.TAF7L modulates brown adipose tissue formation.Mechanism and evolution of cytosolic Hedgehog signal transductionMediator and human diseaseMediator subunit 12 is required for neutrophil development in zebrafishYin and yang of mediator function revealed by human mutantsThe Kto-Skd complex can regulate ptc expression by interacting with Cubitus interruptus (Ci) in the Hedgehog signaling pathway.MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas.Requirements for mediator complex subunits distinguish three classes of notch target genes at the Drosophila wing marginMultisite interaction with Sufu regulates Ci/Gli activity through distinct mechanisms in Hh signal transduction.Distinct roles for Mediator Cdk8 module subunits in Drosophila development.Nonsyndromic X-linked intellectual deficiency in three brothers with a novel MED12 missense mutation [c.5922G>T (p.Glu1974His)].Mediator subunit Med12 contributes to the maintenance of neural stem cell identity.MED12 methylation by CARM1 sensitizes human breast cancer cells to chemotherapy drugsDual functions of TAF7L in adipocyte differentiation.Pygopus activates Wingless target gene transcription through the mediator complex subunits Med12 and Med13.Mutations in MED12 cause X-linked Ohdo syndromeMultiple roles for Med12 in vertebrate endoderm development.Vitamin D3 Inhibits Wnt/β-Catenin and mTOR Signaling Pathways in Human Uterine Fibroid CellsMediator links epigenetic silencing of neuronal gene expression with x-linked mental retardationWnt signaling targets ETO coactivation domain of TAF4/TFIID in vivoMessage in a nucleus: signaling to the transcriptional machineryGenetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness.MED12 mutations in breast phyllodes tumors: evidence of temporal tumoral heterogeneity and identification of associated critical signaling pathwaysGene-specific transcription activation via long-range allosteric shape-shifting.Recent developments in uterine mesenchymal neoplasms.MED12 regulates a transcriptional network of calcium-handling genes in the heart.Silencing Med12 Gene Reduces Proliferation of Human Leiomyoma Cells Mediated via Wnt/β-Catenin Signaling Pathway.
P2860
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P2860
Mediator modulates Gli3-dependent Sonic hedgehog signaling
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Mediator modulates Gli3-dependent Sonic hedgehog signaling
@ast
Mediator modulates Gli3-dependent Sonic hedgehog signaling
@en
Mediator modulates Gli3-dependent Sonic hedgehog signaling
@nl
type
label
Mediator modulates Gli3-dependent Sonic hedgehog signaling
@ast
Mediator modulates Gli3-dependent Sonic hedgehog signaling
@en
Mediator modulates Gli3-dependent Sonic hedgehog signaling
@nl
prefLabel
Mediator modulates Gli3-dependent Sonic hedgehog signaling
@ast
Mediator modulates Gli3-dependent Sonic hedgehog signaling
@en
Mediator modulates Gli3-dependent Sonic hedgehog signaling
@nl
P2093
P2860
P921
P3181
P356
P1476
Mediator modulates Gli3-dependent Sonic hedgehog signaling
@en
P2093
Haiying Zhou
Seokjoong Kim
Thomas G Boyer
P2860
P304
P3181
P356
10.1128/MCB.00443-06
P407
P577
2006-09-25T00:00:00Z