Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study
about
Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's diseaseApolipoprotein E and Alzheimer diseaseCerebrospinal Fluid Particles in Alzheimer Disease and Parkinson DiseaseStable expression and secretion of apolipoproteins E3 and E4 in mouse neuroblastoma cells produces differential effects on neurite outgrowthMorphological, Biochemical, and Genetic Support for an Apolipoprotein E Effect on Microtubular MetabolismaIsoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females.Malaria circumsporozoite protein inhibits protein synthesis in mammalian cells.Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicityApolipoprotein E: from lipid transport to neurobiologyFunction and comorbidities of apolipoprotein e in Alzheimer's disease.Activation of estrogen receptor alpha increases and estrogen receptor beta decreases apolipoprotein E expression in hippocampus in vitro and in vivo.Introducing Human APOE into Aβ Transgenic Mouse Models.Specific regional transcription of apolipoprotein E in human brain neuronsProminent axonopathy and disruption of axonal transport in transgenic mice expressing human apolipoprotein E4 in neurons of brain and spinal cord.Impairments in spatial memory retention of GFAP-apoE4 female mice.Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic miceApolipoprotein E and cholesterol in aging and disease in the brainApolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neuronsNeuronal cell death in Alzheimer's disease correlates with apoE uptake and intracellular Abeta stabilization.Fleshing out the amyloid cascade hypothesis: the molecular biology of Alzheimer's disease.Stabilization of intracellular trafficking and metabolism of amyloid β-protein precursor and Alcadein β by apolipoprotein E.APOE and CYP2E1 polymorphisms, alcohol consumption, and Parkinson's disease in a Japanese population.Sodium dodecyl sulfate-resistant complexes of Alzheimer's amyloid beta-peptide with the N-terminal, receptor binding domain of apolipoprotein E.Proteins in unexpected locations.Apolipoprotein E4 domain interaction occurs in living neuronal cells as determined by fluorescence resonance energy transfer.Astroglial regulation of apolipoprotein E expression in neuronal cells. Implications for Alzheimer's disease.Clinical and neuropathological correlates of apolipoprotein E genotype in Alzheimer's disease. Window on molecular epidemiology.Apolipoprotein E, synaptic plasticity and Alzheimer's disease.The inhibitory effect of apolipoprotein E4 on neurite outgrowth is associated with microtubule depolymerization.Apolipoprotein E structural requirements for the formation of SDS-stable complexes with beta-amyloid-(1-40): the role of salt bridges.Aβ internalization by neurons and glia.The number of cysteine residues per mole in apolipoprotein E affects systematically synchronous neural interactions in women's healthy brains.Roles of apolipoprotein E4 (ApoE4) in the pathogenesis of Alzheimer's disease: lessons from ApoE mouse models.Differential cellular accumulation/retention of apolipoprotein E mediated by cell surface heparan sulfate proteoglycans. Apolipoproteins E3 and E2 greater than e4.Preferential transfer of 2-docosahexaenoyl-1-lysophosphatidylcholine through an in vitro blood-brain barrier over unesterified docosahexaenoic acid.Apolipoprotein E and the CNS response to injury.Apolipoprotein E isoform-specific differences in outcome from focal ischemia in transgenic mice.Apolipoprotein E immunoreactivity in neurons and neurofibrillary degeneration of aged non-demented and Alzheimer's disease patients.Astrocytes down-regulate neuronal beta-amyloid precursor protein expression and modify its processing in an apolipoprotein E isoform-specific manner.Endogenous Apolipoprotein E (ApoE) Fragmentation Is Linked to Amyloid Pathology in Transgenic Mouse Models of Alzheimer's Disease.
P2860
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P2860
Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study
description
1994 nî lūn-bûn
@nan
1994 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Apolipoprotein E is localized ...... and electron microscopic study
@ast
Apolipoprotein E is localized ...... and electron microscopic study
@en
Apolipoprotein E is localized ...... and electron microscopic study
@en-gb
Apolipoprotein E is localized ...... and electron microscopic study
@nl
type
label
Apolipoprotein E is localized ...... and electron microscopic study
@ast
Apolipoprotein E is localized ...... and electron microscopic study
@en
Apolipoprotein E is localized ...... and electron microscopic study
@en-gb
Apolipoprotein E is localized ...... and electron microscopic study
@nl
prefLabel
Apolipoprotein E is localized ...... and electron microscopic study
@ast
Apolipoprotein E is localized ...... and electron microscopic study
@en
Apolipoprotein E is localized ...... and electron microscopic study
@en-gb
Apolipoprotein E is localized ...... and electron microscopic study
@nl
P2093
P1476
Apolipoprotein E is localized ...... and electron microscopic study
@en
P2093
A M Saunders
D E Schmechel
G Einstein
K H Weisgraber
M Pericak-Vance
W J Strittmatter
P304
P356
10.1097/00005072-199409000-00013
P407
P577
1994-09-01T00:00:00Z