Enhanced hematopoiesis by hematopoietic progenitor cells lacking intracellular adaptor protein, Lnk
about
The adapter protein APS associates with the multifunctional docking sites Tyr-568 and Tyr-936 in c-KitSH2-B is required for both male and female reproductionSpred-2 suppresses aorta-gonad-mesonephros hematopoiesis by inhibiting MAP kinase activationOntological visualization of protein-protein interactionsThe role of small adaptor proteins in the control of oncogenic signalingr driven by tyrosine kinases in human cancerThe secret life of a megakaryocyte: emerging roles in bone marrow homeostasis controlThe adaptor molecule Lnk negatively regulates tumor necrosis factor-alpha-dependent VCAM-1 expression in endothelial cells through inhibition of the ERK1 and -2 pathwaysAdaptor protein Lnk inhibits c-Fms-mediated macrophage functionLnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transductionLnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathwaysLnk controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2Targeted mutations of the juxtamembrane tyrosines in the Kit receptor tyrosine kinase selectively affect multiple cell lineagesRegulation of hematopoietic development in the aorta-gonad-mesonephros region mediated by Lnk adaptor proteinIncreased numbers of B-1 cells and enhanced responses against TI-2 antigen in mice lacking APS, an adaptor molecule containing PH and SH2 domainsLnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo.Stem and progenitor cell subsets are affected by JAK2 signaling and can be monitored by flow cytometry.Pathological interactions between hematopoietic stem cells and their niche revealed by mouse models of primary myelofibrosis.Octa-arginine mediated delivery of wild-type Lnk protein inhibits TPO-induced M-MOK megakaryoblastic leukemic cell growth by promoting apoptosis.Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells by way of teratoma formation.Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms.Lnk-dependent axis of SCF-cKit signal for osteogenesis in bone fracture healing.LNK (SH2B3): paradoxical effects in ovarian cancer.Reduced repression of cytokine signaling ameliorates age-induced decline in hematopoietic stem cell function.Generation and homing of iPSC-derived hematopoietic cells in vivoSpred-1 negatively regulates interleukin-3-mediated ERK/mitogen-activated protein (MAP) kinase activation in hematopoietic cells.ROS-mediated amplification of AKT/mTOR signalling pathway leads to myeloproliferative syndrome in Foxo3(-/-) mice.A small interfering RNA targeting Lnk accelerates bone fracture healing with early neovascularization.Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK.Recent findings in the genetics of blood pressure and hypertension traits.Adaptors as central mediators of signal transduction in immune cells.Making a Hematopoietic Stem Cell14-3-3 regulates the LNK/JAK2 pathway in mouse hematopoietic stem and progenitor cellsAdaptor protein Lnk binds to and inhibits normal and leukemic FLT3.Stem cell factor expression, mast cells and inflammation in asthma.Alcohol Consumption Modulates Host Defense in Rhesus Macaques by Altering Gene Expression in Circulating Leukocytes.Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis.Total and Differential Leukocyte Counts in Relation to Incidence of Diabetes Mellitus: A Prospective Population-Based Cohort StudyComprehensive review of JAK inhibitors in myeloproliferative neoplasms.Overlap between common genetic polymorphisms underpinning kidney traits and cardiovascular disease phenotypes: the CKDGen consortiumNormal and malignant megakaryopoiesis.
P2860
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P2860
Enhanced hematopoiesis by hematopoietic progenitor cells lacking intracellular adaptor protein, Lnk
description
2002 nî lūn-bûn
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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2002 թվականի հունվարին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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Enhanced hematopoiesis by hema ...... acellular adaptor protein, Lnk
@ast
Enhanced hematopoiesis by hema ...... acellular adaptor protein, Lnk
@en
Enhanced hematopoiesis by hema ...... acellular adaptor protein, Lnk
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Enhanced hematopoiesis by hema ...... acellular adaptor protein, Lnk
@ast
Enhanced hematopoiesis by hema ...... acellular adaptor protein, Lnk
@en
Enhanced hematopoiesis by hema ...... acellular adaptor protein, Lnk
@nl
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Enhanced hematopoiesis by hema ...... acellular adaptor protein, Lnk
@ast
Enhanced hematopoiesis by hema ...... acellular adaptor protein, Lnk
@en
Enhanced hematopoiesis by hema ...... acellular adaptor protein, Lnk
@nl
P2093
P2860
P921
P356
P1476
Enhanced hematopoiesis by hema ...... acellular adaptor protein, Lnk
@en
P2093
Hatsue Morita
Kiyoshi Takatsu
Satoshi Takaki
Yoshinari Tezuka
P2860
P304
P356
10.1084/JEM.20011170
P407
P577
2002-01-21T00:00:00Z