General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH
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Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase at 1.0 Å resolution - a potential target for anti-tuberculosis drug discoveryAn Ancient Fingerprint Indicates the Common Ancestry of Rossmann-Fold Enzymes Utilizing Different Ribose-Based CofactorsEnhancing the light-driven production of D-lactate by engineering cyanobacterium using a combinational strategyEngineering Nucleotide Specificity of Succinyl-CoA Synthetase in Blastocystis: The Emerging Role of Gatekeeper ResiduesSubstitutions at the cofactor phosphate-binding site of a clostridial alcohol dehydrogenase lead to unexpected changes in substrate specificity.Mutations in adenine-binding pockets enhance catalytic properties of NAD(P)H-dependent enzymes.Cofactor specificity motifs and the induced fit mechanism in class I ketol-acid reductoisomerases.High-Throughput Screening of Coenzyme Preference Change of Thermophilic 6-Phosphogluconate Dehydrogenase from NADP(+) to NAD(.).Coenzyme Engineering of a Hyperthermophilic 6-Phosphogluconate Dehydrogenase from NADP(+) to NAD(+) with Its Application to Biobatteries.Metalloenzyme design and engineering through strategic modifications of native protein scaffolds.Recent advances in engineering proteins for biocatalysis.The Need for Integrated Approaches in Metabolic Engineering.Tryptophan Synthase Uses an Atypical Mechanism To Achieve Substrate Specificity.Switch in Cofactor Specificity of a Baeyer-Villiger Monooxygenase.A Panel of TrpB Biocatalysts Derived from Tryptophan Synthase through the Transfer of Mutations that Mimic Allosteric Activation.Extracellular Streptomyces lividans vesicles: composition, biogenesis and antimicrobial activity.Structure-based conversion of the coenzyme requirement of a short-chain dehydrogenase/reductase involved in bacterial alginate metabolism.Artificial domain duplication replicates evolutionary history of ketol-acid reductoisomerases.Protein engineering of oxidoreductases utilizing nicotinamide-based coenzymes, with applications in synthetic biology.Biological Functions of ilvC in Branched-Chain Fatty Acid Synthesis and Diffusible Signal Factor Family Production in Xanthomonas campestris.Bacterial Branched-Chain Amino Acid Biosynthesis: Structures, Mechanisms, and Drugability.Crystal Structures of Staphylococcus aureus Ketol-Acid Reductoisomerase in Complex with Two Transition State Analogues that Have Biocidal Activity.Engineering the cofactor specificity of an alcohol dehydrogenase via single mutations or insertions distal to the 2'-phosphate group of NADP(H).Protein Engineering for Nicotinamide Coenzyme Specificity in Oxidoreductases: Attempts and Challenges.In silico model-driven cofactor engineering strategies for improving the overall NADP(H) turnover in microbial cell factories.Metal Ions Play an Essential Catalytic Role in the Mechanism of Ketol-Acid Reductoisomerase.NADH/NADPH bi-cofactor-utilizing and thermoactive ketol-acid reductoisomerase from Sulfolobus acidocaldarius.
P2860
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P2860
General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH
description
2013 nî lūn-bûn
@nan
2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
General approach to reversing ...... dependence from NADPH to NADH
@ast
General approach to reversing ...... dependence from NADPH to NADH
@en
General approach to reversing ...... dependence from NADPH to NADH
@nl
type
label
General approach to reversing ...... dependence from NADPH to NADH
@ast
General approach to reversing ...... dependence from NADPH to NADH
@en
General approach to reversing ...... dependence from NADPH to NADH
@nl
prefLabel
General approach to reversing ...... dependence from NADPH to NADH
@ast
General approach to reversing ...... dependence from NADPH to NADH
@en
General approach to reversing ...... dependence from NADPH to NADH
@nl
P2093
P2860
P50
P3181
P356
P1476
General approach to reversing ...... dependence from NADPH to NADH
@en
P2093
Eric M Brustad
Jackson K B Cahn
John A McIntosh
Liang Zhang
Peter Meinhold
Tilman Flock
P2860
P304
P3181
P356
10.1073/PNAS.1306073110
P407
P577
2013-07-02T00:00:00Z