Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease
about
Arginine residues 47 and 70 of human flap endonuclease-1 are involved in DNA substrate interactions and cleavage site determinationThe structural and biochemical characterization of human RNase H2 complex reveals the molecular basis for substrate recognition and Aicardi-Goutières syndrome defectsIdling by DNA polymerase delta maintains a ligatable nick during lagging-strand DNA replicationThe 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instabilityOkazaki fragment maturation: nucleases take centre stageComparative genomics and molecular dynamics of DNA repeats in eukaryotesSynergistic defect in 60S ribosomal subunit assembly caused by a mutation of Rrs1p, a ribosomal protein L11-binding protein, and 3'-extension of 5S rRNA in Saccharomyces cerevisiaeA network of multi-tasking proteins at the DNA replication fork preserves genome stabilityA 4-year-old Amish boy with weakness, arthritis, rash, verbal delay, and failure to thriveThe Structure of the Mammalian RNase H2 Complex Provides Insight into RNA{middle dot}DNA Hybrid Processing to Prevent Immune DysfunctionCrystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and CleavagePCNA directs type 2 RNase H activity on DNA replication and repair substratesStructure and characterization of RNase H3 from Aquifex aeolicusRNase H2 of Saccharomyces cerevisiae is a complex of three proteins.The absence of ribonuclease H1 or H2 alters the sensitivity of Saccharomyces cerevisiae to hydroxyurea, caffeine and ethyl methanesulphonate: implications for roles of RNases H in DNA replication and repair.Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAs in yeast.Genetic interactions between HNT3/Aprataxin and RAD27/FEN1 suggest parallel pathways for 5' end processing during base excision repairAn N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks.Analysis of subunit assembly and function of the Saccharomyces cerevisiae RNase H2 complex.Search for apoptotic nucleases in yeast: role of Tat-D nuclease in apoptotic DNA degradation.Cooperativity of Mus81.Mms4 with Rad54 in the resolution of recombination and replication intermediates.Mechanisms employed by Escherichia coli to prevent ribonucleotide incorporation into genomic DNA by Pol VThe deletion of rnhB in Mycobacterium smegmatis does not affect the level of RNase HII substrates or influence genome stabilityRibonucleotides in DNA: Origins, repair and consequencesThe protein components and mechanism of eukaryotic Okazaki fragment maturation.On the roles of Saccharomyces cerevisiae Dna2p and Flap endonuclease 1 in Okazaki fragment processing.Cell cycle-dependent and DNA damage-inducible nuclear localization of FEN-1 nuclease is consistent with its dual functions in DNA replication and repair.Processing ribonucleotides incorporated during eukaryotic DNA replication.Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases.RNaseH2 mutants that cause Aicardi-Goutieres syndrome are active nucleasesMutational spectrum analysis of RNase H(35) deficient Saccharomyces cerevisiae using fluorescence-based directed termination PCR.Genome instability due to ribonucleotide incorporation into DNA.How the misincorporation of ribonucleotides into genomic DNA can be both harmful and helpful to cellsCleavage of double-stranded RNA by RNase HI from a thermoacidophilic archaeon, Sulfolobus tokodaii 7.Acquisition of an Archaea-like ribonuclease H domain by plant L1 retrotransposons supports modular evolutionExcision of misincorporated ribonucleotides in DNA by RNase H (type 2) and FEN-1 in cell-free extracts.Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection.Functional consequences of the RNase H2A subunit mutations that cause Aicardi-Goutieres syndrome.Epistasis analysis between homologous recombination genes in Saccharomyces cerevisiae identifies multiple repair pathways for Sgs1, Mus81-Mms4 and RNase H2Effect of the disease-causing mutations identified in human ribonuclease (RNase) H2 on the activities and stabilities of yeast RNase H2 and archaeal RNase HII.
P2860
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P2860
Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Saccharomyces cerevisiae RNase ...... ooperation with Rad27 nuclease
@ast
Saccharomyces cerevisiae RNase ...... ooperation with Rad27 nuclease
@en
Saccharomyces cerevisiae RNase ...... operation with Rad27 nuclease.
@nl
type
label
Saccharomyces cerevisiae RNase ...... ooperation with Rad27 nuclease
@ast
Saccharomyces cerevisiae RNase ...... ooperation with Rad27 nuclease
@en
Saccharomyces cerevisiae RNase ...... operation with Rad27 nuclease.
@nl
altLabel
Saccharomyces cerevisiae RNase ...... ooperation with Rad27 nuclease
@en
prefLabel
Saccharomyces cerevisiae RNase ...... ooperation with Rad27 nuclease
@ast
Saccharomyces cerevisiae RNase ...... ooperation with Rad27 nuclease
@en
Saccharomyces cerevisiae RNase ...... operation with Rad27 nuclease.
@nl
P2093
P2860
P356
P1476
Saccharomyces cerevisiae RNase ...... ooperation with Rad27 nuclease
@en
P2093
P2860
P304
P356
10.1128/MCB.19.12.8361
P407
P577
1999-12-01T00:00:00Z