Cloning of the cDNA encoding the large subunit of human RNase HI, a homologue of the prokaryotic RNase HII
about
The structural and biochemical characterization of human RNase H2 complex reveals the molecular basis for substrate recognition and Aicardi-Goutières syndrome defectsAicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunityStructure and dynamics of thioguanine-modified duplex DNAThe Structure of the Mammalian RNase H2 Complex Provides Insight into RNA{middle dot}DNA Hybrid Processing to Prevent Immune DysfunctionCrystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and CleavagePCNA directs type 2 RNase H activity on DNA replication and repair substratesRNase H2 of Saccharomyces cerevisiae is a complex of three proteins.Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nucleasePurification of Saccharomyces cerevisiae RNase H(70) and identification of the corresponding gene.The hepatitis B virus ribonuclease H is sensitive to inhibitors of the human immunodeficiency virus ribonuclease H and integrase enzymesHuman RNase H1 is associated with protein P32 and is involved in mitochondrial pre-rRNA processingNew roles for the major human 3'-5' exonuclease TREX1 in human disease.Eukaryotic ribonucleases HI and HII generate characteristic hydrolytic patterns on DNA-RNA hybrids: further evidence that mitochondrial RNase H is an RNase HII.Mutational spectrum analysis of RNase H(35) deficient Saccharomyces cerevisiae using fluorescence-based directed termination PCR.Properties of cloned and expressed human RNase H1.The involvement of human ribonucleases H1 and H2 in the variation of response of cells to antisense phosphorothioate oligonucleotides.Human RNase H1 activity is regulated by a unique redox switch formed between adjacent cysteines.Human RNase H1 uses one tryptophan and two lysines to position the enzyme at the 3'-DNA/5'-RNA terminus of the heteroduplex substrate.Potential roles of antisense technology in cancer chemotherapy.Determination of the role of the human RNase H1 in the pharmacology of DNA-like antisense drugs.Excision of misincorporated ribonucleotides in DNA by RNase H (type 2) and FEN-1 in cell-free extracts.Ribonuclease H2 in health and disease.Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection.Increased efficacy of antileishmanial antisense phosphorothioate oligonucleotides in Leishmania amazonensis overexpressing ribonuclease HFunctional consequences of the RNase H2A subunit mutations that cause Aicardi-Goutieres syndrome.Ribonuclease H: the enzymes in eukaryotesSelective inhibitory DNA aptamers of the human RNase H1Transcriptional responses to loss of RNase H2 in Saccharomyces cerevisiae.Dna2 on the road to Okazaki fragment processing and genome stability in eukaryotes.Investigating the structure of human RNase H1 by site-directed mutagenesis.
P2860
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P2860
Cloning of the cDNA encoding the large subunit of human RNase HI, a homologue of the prokaryotic RNase HII
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Cloning of the cDNA encoding t ...... e of the prokaryotic RNase HII
@ast
Cloning of the cDNA encoding t ...... e of the prokaryotic RNase HII
@en
Cloning of the cDNA encoding t ...... e of the prokaryotic RNase HII
@en-gb
Cloning of the cDNA encoding t ...... e of the prokaryotic RNase HII
@nl
type
label
Cloning of the cDNA encoding t ...... e of the prokaryotic RNase HII
@ast
Cloning of the cDNA encoding t ...... e of the prokaryotic RNase HII
@en
Cloning of the cDNA encoding t ...... e of the prokaryotic RNase HII
@en-gb
Cloning of the cDNA encoding t ...... e of the prokaryotic RNase HII
@nl
prefLabel
Cloning of the cDNA encoding t ...... e of the prokaryotic RNase HII
@ast
Cloning of the cDNA encoding t ...... e of the prokaryotic RNase HII
@en
Cloning of the cDNA encoding t ...... e of the prokaryotic RNase HII
@en-gb
Cloning of the cDNA encoding t ...... e of the prokaryotic RNase HII
@nl
P2093
P2860
P356
P1476
Cloning of the cDNA encoding t ...... e of the prokaryotic RNase HII
@en
P2093
C Braunshofer-Reiter
U Wintersberger
P2860
P304
P356
10.1073/PNAS.95.22.12872
P407
P577
1998-10-27T00:00:00Z