Dimerization choices control the ability of axin and dishevelled to activate c-Jun N-terminal kinase/stress-activated protein kinase
about
Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signalingI-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways.The links between axin and carcinogenesisAxin utilizes distinct regions for competitive MEKK1 and MEKK4 binding and JNK activationCasein kinase I and casein kinase II differentially regulate axin function in Wnt and JNK pathwaysThe DIX domain protein coiled-coil-DIX1 inhibits c-Jun N-terminal kinase activation by Axin and dishevelled through distinct mechanismsBoth the RGS domain and the six C-terminal amino acids of mouse Axin are required for normal embryogenesisAxin contains three separable domains that confer intramolecular, homodimeric, and heterodimeric interactions involved in distinct functionsProtein encoded by the Axin(Fu) allele effectively down-regulates Wnt signaling but exerts a dominant negative effect on c-Jun N-terminal kinase signalingModulation of the beta-catenin signaling pathway by the dishevelled-associated protein Hipk1.Axin1 prevents Salmonella invasiveness and inflammatory response in intestinal epithelial cellsIntrinsic disorder in scaffold proteins: getting more from lessNetwork topologies and convergent aetiologies arising from deletions and duplications observed in individuals with autism.Dishevelled activates Ca2+ flux, PKC, and CamKII in vertebrate embryos.Crystallization and preliminary X-ray crystallographic studies of the axin DIX domainDiversity of axin in signaling pathways and its relation to colorectal cancer.Differential molecular assemblies underlie the dual function of Axin in modulating the WNT and JNK pathways.MAP3K1 functionally interacts with Axin1 in the canonical Wnt signalling pathway.A role for planar cell polarity signaling in angiogenesis.Differential requirement of MKK4 and MKK7 in JNK activation by distinct scaffold proteins.Glycogen synthase kinase 3 beta is a natural activator of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 1 (MEKK1).Regulation of Akt and Wnt signaling by the group II metabotropic glutamate receptor antagonist LY341495 and agonist LY379268.
P2860
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P2860
Dimerization choices control the ability of axin and dishevelled to activate c-Jun N-terminal kinase/stress-activated protein kinase
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Dimerization choices control t ...... tress-activated protein kinase
@ast
Dimerization choices control t ...... tress-activated protein kinase
@en
Dimerization choices control t ...... tress-activated protein kinase
@nl
type
label
Dimerization choices control t ...... tress-activated protein kinase
@ast
Dimerization choices control t ...... tress-activated protein kinase
@en
Dimerization choices control t ...... tress-activated protein kinase
@nl
prefLabel
Dimerization choices control t ...... tress-activated protein kinase
@ast
Dimerization choices control t ...... tress-activated protein kinase
@en
Dimerization choices control t ...... tress-activated protein kinase
@nl
P2093
P2860
P356
P1476
Dimerization choices control t ...... tress-activated protein kinase
@en
P2093
P2860
P304
P356
10.1074/JBC.M002491200
P407
P577
2000-08-11T00:00:00Z