Hyaluronan promotes CD44v3-Vav2 interaction with Grb2-p185(HER2) and induces Rac1 and Ras signaling during ovarian tumor cell migration and growth
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Hyaluronan-mediated CD44 interaction with p300 and SIRT1 regulates beta-catenin signaling and NFkappaB-specific transcription activity leading to MDR1 and Bcl-xL gene expression and chemoresistance in breast tumor cellsHyaluronan-CD44 interaction promotes c-Src-mediated twist signaling, microRNA-10b expression, and RhoA/RhoC up-regulation, leading to Rho-kinase-associated cytoskeleton activation and breast tumor cell invasionCD44 variant isoforms in head and neck squamous cell carcinoma progressionApproaches of targeting Rho GTPases in cancer drug discoveryEGFR/HER-targeted therapeutics in ovarian cancerInteractions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and CancerThe catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodesInteraction of low molecular weight hyaluronan with CD44 and toll-like receptors promotes the actin filament-associated protein 110-actin binding and MyD88-NFκB signaling leading to proinflammatory cytokine/chemokine production and breast tumor invaPotassium-chloride cotransporter 3 interacts with Vav2 to synchronize the cell volume decrease response with cell protrusion dynamics.Abrogating drug resistance in malignant peripheral nerve sheath tumors by disrupting hyaluronan-CD44 interactions with small hyaluronan oligosaccharides.Hyaluronan, CD44, and emmprin regulate lactate efflux and membrane localization of monocarboxylate transporters in human breast carcinoma cellsInhibition of Functional Hyaluronan-CD44 Interactions in CD133-positive Primary Human Ovarian Carcinoma Cells by Small Hyaluronan Oligosaccharides.Matrix hyaluronan alters epidermal growth factor receptor-dependent cell morphologyCD44: a novel synaptic cell adhesion molecule regulating structural and functional plasticity of dendritic spines.CD44 gene polymorphisms and environmental factors on oral cancer susceptibility in TaiwanReduction of hyaluronan-CD44-mediated growth, migration, and cisplatin resistance in head and neck cancer due to inhibition of Rho kinase and PI-3 kinase signaling.Integrative network analysis reveals active microRNAs and their functions in gastric cancer.Overexpression of CD44 accompanies acquired tamoxifen resistance in MCF7 cells and augments their sensitivity to the stromal factors, heregulin and hyaluronan.Potentially important microRNA cluster on chromosome 17p13.1 in primary peritoneal carcinoma.Role of versican, hyaluronan and CD44 in ovarian cancer metastasis.Hyaluronan oligosaccharides induce matrix metalloproteinase 13 via transcriptional activation of NFkappaB and p38 MAP kinase in articular chondrocytes.Vav2 protein overexpression marks and may predict the aggressive subtype of ductal carcinoma in situA novel nuclear role for the Vav3 nucleotide exchange factor in androgen receptor coactivation in prostate cancerCardiac chamber formation: development, genes, and evolution.Molecular Mechanisms of Trastuzumab Resistance in HER2 Overexpressing Breast CancerMicroneedle fractional radiofrequency increases epidermal hyaluronan and reverses age-related epidermal dysfunction.Cleavage of Hyaluronan and CD44 Adhesion Molecule Regulate Astrocyte Morphology via Rac1 Signalling.The effect of soluble E-selectin on tumor progression and metastasis.Hyaluronan: a critical component of epithelial-mesenchymal and epithelial-carcinoma transitions.Resistance to Trastuzumab in Breast Cancer.Expression and Function of CD44 in Epithelial Ovarian CarcinomaLipid raft association restricts CD44-ezrin interaction and promotion of breast cancer cell migration.Acquired resistance of pancreatic cancer cells to treatment with gemcitabine and HER-inhibitors is accompanied by increased sensitivity to STAT3 inhibition.Hyaluronan as a therapeutic target in human diseasesHyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells.Hyaluronan, CD44 and Emmprin: partners in cancer cell chemoresistance.Hyaluronan-mediated CD44 activation of RhoGTPase signaling and cytoskeleton function promotes tumor progression.Hyaluronan, CD44, and cyclooxygenase-2 in colon cancer.The soluble Decoy Receptor 3 is regulated by a PI3K-dependent mechanism and promotes migration and invasion in renal cell carcinoma.Hyaluronan-CD44 interaction with protein kinase C(epsilon) promotes oncogenic signaling by the stem cell marker Nanog and the Production of microRNA-21, leading to down-regulation of the tumor suppressor protein PDCD4, anti-apoptosis, and chemothera
P2860
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P2860
Hyaluronan promotes CD44v3-Vav2 interaction with Grb2-p185(HER2) and induces Rac1 and Ras signaling during ovarian tumor cell migration and growth
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Hyaluronan promotes CD44v3-Vav ...... umor cell migration and growth
@ast
Hyaluronan promotes CD44v3-Vav ...... umor cell migration and growth
@en
Hyaluronan promotes CD44v3-Vav ...... umor cell migration and growth
@nl
type
label
Hyaluronan promotes CD44v3-Vav ...... umor cell migration and growth
@ast
Hyaluronan promotes CD44v3-Vav ...... umor cell migration and growth
@en
Hyaluronan promotes CD44v3-Vav ...... umor cell migration and growth
@nl
prefLabel
Hyaluronan promotes CD44v3-Vav ...... umor cell migration and growth
@ast
Hyaluronan promotes CD44v3-Vav ...... umor cell migration and growth
@en
Hyaluronan promotes CD44v3-Vav ...... umor cell migration and growth
@nl
P2093
P2860
P3181
P356
P1476
Hyaluronan promotes CD44v3-Vav ...... umor cell migration and growth
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.M106759200
P407
P577
2001-12-28T00:00:00Z