Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types - sprookjes - yvandenbroek - TriplyDB

Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types

Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types

http://www.wikidata.org/entity/Q28214927

about

sameAs

Anaplastic lymphoma kinase: signalling in development and disease Lung cancer cell migration is regulated via repressing growth factor PTN/RPTP β/ζ signaling by menin Correlation of elevated level of blood midkine with poor prognostic factors of human neuroblastomas Molecular mechanisms that underpin EML4-ALK driven cancers and their response to targeted drugs ALK and ROS1 as targeted therapy paradigms and clinical implications to overcome crizotinib resistance Emerging importance of ALK in neuroblastoma Midkine in host defence Midkine and cytoplasmic maturation of mammalian oocytes in the context of ovarian follicle physiology Structure and function of midkine as the basis of its pharmacological effects Involvement of midkine in neuroblastoma tumourigenesis Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma Identification of midkine as a mediator for intercellular transfer of drug resistance Molecular pathogenesis of peripheral neuroblastic tumors Pleiotrophin inhibits HIV infection by binding the cell surface-expressed nucleolin ALK activation induces Shc and FRS2 recruitment: Signaling and phenotypic outcomes in PC12 cells differentiation Anaplastic lymphoma kinase activates the small GTPase Rap1 via the Rap1-specific GEF C3G in both neuroblastoma and PC12 cells Mutation-introduced dimerization of receptor tyrosine kinases: from protein structure aberrations to carcinogenesis.Concordant morphologic and gene expression data show that a vaccine halts HER-2/neu preneoplastic lesions Transcriptome profiling of the tubular porcine conceptus identifies the differential regulation of growth and developmentally associated genes.Effect of single-chain antibody targeting of the ligand-binding domain in the anaplastic lymphoma kinase receptor.Global gene expression profiling of human pleural mesotheliomas: identification of matrix metalloproteinase 14 (MMP-14) as potential tumour target Mystic Acetaldehyde: The Never-Ending Story on Alcoholism ALK-rearrangements and testing methods in non-small cell lung cancer: a review The synthetic peptide P111-136 derived from the C-terminal domain of heparin affin regulatory peptide inhibits tumour growth of prostate cancer PC-3 cells.ALK-activating homologous mutations in LTK induce cellular transformation.Signaling receptome: a genomic and evolutionary perspective of plasma membrane receptors involved in signal transduction.Chromogenic in situ hybridization is a reliable assay for detection of ALK rearrangements in adenocarcinomas of the lung.The preclinical profile of crizotinib for the treatment of non-small-cell lung cancer and other neoplastic disorders.Pleiotrophin (PTN) expression and function and in the mouse mammary gland and mammary epithelial cells.The Drosophila midkine/pleiotrophin homologues Miple1 and Miple2 affect adult lifespan but are dispensable for alk signaling during embryonic gut formation.Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome.Anaplastic lymphoma kinase is a dependence receptor whose proapoptotic functions are activated by caspase cleavage.Pleiotrophin as a central nervous system neuromodulator, evidences from the hippocampus.Identification of anaplastic lymphoma kinase as a potential therapeutic target in Basal Cell Carcinoma Transcriptional factor specificity protein 1 (SP1) promotes the proliferation of glioma cells by up-regulating midkine (MDK).Genetic and functional studies implicate synaptic overgrowth and ring gland cAMP/PKA signaling defects in the Drosophila melanogaster neurofibromatosis-1 growth deficiency.Biological role of anaplastic lymphoma kinase in neuroblastoma.Pleiotrophin commits human bone marrow mesenchymal stromal cells towards hypertrophy during chondrogenesis

P2860

Q24312329-DB170B8D-7F2A-4B15-AC13-82D09D63CEB6 Q24339039-66DB90B1-BD2F-4FFC-93C4-FEDBD91DFA5B Q24656678-C6FD3108-8C08-41A8-A234-E13DCF13CB90 Q26769659-81B2BE20-3120-428C-B292-E02FDD2B5FBD Q26775347-F0662763-B054-4699-BBD1-B0E7C293639F Q26858819-D5A32E98-6CCE-446B-B109-EC551BFF6FC6 Q27010045-CA53DFA6-9ECC-4060-A14E-17970C684211 Q27010676-9730BAC4-C065-4795-ADA3-1B6B1C562E89 Q27013798-0A27AB31-6B11-440C-861A-424BCB09FFAB Q27026748-369C36CE-3265-4FE6-9EB0-670A98523B4F Q27663479-C59FD663-450D-4F90-B9B8-791B40380D34 Q28118071-6902EC8F-69EB-4798-8903-077257FDA73C Q28206624-F86964B3-1D93-48FD-9AC8-D9C49CBB0AF3 Q28251166-F23923FD-09E5-4165-8DA7-8E689A52611C Q28271405-A162AF83-8712-44EB-87D7-28D49A19C931 Q28271787-BA7BDFDA-8CA0-44B6-A49D-4E54F3F8FB6E Q28564190-8A742D03-998C-4E16-B9EB-7EC36FFDC63B Q28571575-05EC91C7-AAC7-4117-A2D1-17358D4A567D Q30372506-3B1ABC3F-A404-46DC-A76F-D7F17A5CD84B Q30909247-C451F826-7E08-491E-AA24-0715C5E2FBF4 Q33253603-B572DAE7-F921-4575-B2D3-2147777837AC Q33487136-5F957D6E-2A5E-4851-B4D3-C804AD94ABAF Q33503255-493EB685-EB43-4EB0-A920-6C6435E38133 Q33659011-7ACE4997-CD87-4A54-B94C-19E07A8417C9 Q33776835-7D509704-8256-4221-B815-3F35CDA9DFF7 Q33915644-AE5949D8-07DC-4E38-A392-0E367619C81D Q34162940-3F394D46-A87E-42F3-92F3-B2853A8DCC5E Q34207111-DDAD5443-6AAE-4D73-BB5C-A1D158F6BEA6 Q34349164-B6178746-F547-4353-AC31-D58D76FABC18 Q34353920-456CC799-DB83-4C02-915F-23E149E82900 Q34451087-03BAEF98-D23E-43AD-BD5C-2DA3E19C0776 Q34473183-40856A21-73A3-411E-A712-6ABFFF738B8C Q34480771-B155B752-9DDF-4FD6-9969-B84DD8AAB53A Q34552993-29987E20-6F08-4AA3-8A19-5F1B777B28C2 Q34869224-DA68D98C-673A-4836-BFE0-FD04C7AFAC34 Q35026938-91EA32DD-716D-4207-87E2-24523B73CC14 Q35027553-76E8C598-8491-4638-AB2D-3568D4E7C476 Q35053088-B73DF9B1-97FE-4505-81BE-AAF4D86B860D Q35084934-B2AC6521-D17B-4B3B-8AF3-0BAB0B62A6D1 Q35091670-44D92671-5DDB-4C32-9A5C-740C538049B9

P2860

Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types

http://www.wikidata.org/entity/Q28214927

description

2002 nî lūn-bûn

@nan

2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

Midkine binds to anaplastic ly ...... actor for different cell types

@ast

Midkine binds to anaplastic ly ...... actor for different cell types

@en

Midkine binds to anaplastic ly ...... actor for different cell types

@nl

type

label

Midkine binds to anaplastic ly ...... actor for different cell types

@ast

Midkine binds to anaplastic ly ...... actor for different cell types

@en

Midkine binds to anaplastic ly ...... actor for different cell types

@nl

prefLabel

Midkine binds to anaplastic ly ...... actor for different cell types

@ast

Midkine binds to anaplastic ly ...... actor for different cell types

@en

Midkine binds to anaplastic ly ...... actor for different cell types

@nl

P1433

Q28214927-668F1266-180B-478A-90CE-2E50DDDD573C

P1476

Q28214927-496ADA3F-5024-4B1C-A50F-2A7803DFB76A

P2093

Q28214927-5B1E561D-0228-43DB-A6C9-563D70B1F992

Q28214927-9C54C11B-A164-49FB-B98F-ECB7540F3640

Q28214927-B36CC2E1-38E3-40C9-9B19-152CAE2C10EA

Q28214927-C46F2FA1-8000-4ABC-B4B2-0591A42BB955

Q28214927-D288AD4A-9DD6-49F9-8038-B11B9D5C4BEE

Q28214927-D568C2EF-965B-4928-A8C1-2D5D25DD2ADE

P2860

Q28214927-042F7FB3-02AC-4A4F-8F9D-D58D5BB5DC78

Q28214927-08E6C93A-1314-4F26-8BD1-6B0944AC1C8F

Q28214927-0B9A7CC9-C127-4737-AC2D-29749688CEDE

Q28214927-0C6C7402-3BC8-4DEF-9461-7124350548DC

Q28214927-15113348-8498-427F-A7E2-8C20245A3470

Q28214927-153DEDA8-2B40-4FB6-A118-AF242EB5C21E

Q28214927-1C0DA174-9CEA-4884-B120-3416D850D3FC

Q28214927-28ABA919-58B3-4C29-889D-9F767765A2A4

Q28214927-35D2B69F-839D-4A64-9D88-B58E1F5655EA

Q28214927-3E85791E-5DEB-474C-8D3D-9CD0E9BE5BDF

P304

Q28214927-261A2B5B-D571-4D81-9E64-323F58BB8AD6

P31

Q28214927-82258CE4-05A2-4AB7-9EB6-BCEE5EA1B2B5

P3181

Q28214927-3F2155ED-C8C8-473E-8A65-4046868D688E

P356

Q28214927-8D490CEA-D4B2-4D93-BEE8-9BC9E33032C8

P407

Q28214927-3CFD4C49-E3FE-4BB1-85DE-7251B2B876BE

P433

Q28214927-1EB3ACDE-AB4C-4749-8DAD-34324983AB17

P478

Q28214927-7FB5D3B7-BFEA-4DF5-8164-B892D84530B6

P50

Q28214927-7009A727-6456-49A1-BC88-7D886AAADF9C

P577

Q28214927-16BA516F-47D9-4904-90EA-7689E358EC71

P698

Q28214927-A6EA1D10-D979-40D3-8E5F-FC7EDA5D3E26

P3181

P356

P1433

Journal of Biological Chemistry

P1476

Midkine binds to anaplastic ly ...... actor for different cell types

@en

P2093

Angera Kuo

http://www.w3.org/2001/XMLSchema#string

Anna T Riegel

http://www.w3.org/2001/XMLSchema#string

Ciaran Powers

http://www.w3.org/2001/XMLSchema#string

Elaine Buchert Sale

http://www.w3.org/2001/XMLSchema#string

Emma T Bowden

http://www.w3.org/2001/XMLSchema#string

Gerald E Stoica

http://www.w3.org/2001/XMLSchema#string

P2860

Genomic structure of human midkine (MK), a retinoic acid-responsive growth/differentiation factor

Characterization and cDNA cloning of phospholipase C-gamma, a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase

Serum midkine levels are increased in patients with various types of carcinomas

LDL receptor-related protein as a component of the midkine receptor

Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin

Pleiotrophin signaling through anaplastic lymphoma kinase is rate-limiting for glioblastoma growth

Cloning, characterization and developmental regulation of two members of a novel human gene family of neurite outgrowth-promoting proteins

Midkine induces tumor cell proliferation and binds to a high affinity signaling receptor associated with JAK tyrosine kinases

Biochemical and mitogenic properties of the heparin-binding growth factor HARP

Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system

P304

35990-35998

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

3345410

http://www.w3.org/2001/XMLSchema#string

P356

10.1074/JBC.M205749200

http://www.w3.org/2001/XMLSchema#string

P407

P433

39

http://www.w3.org/2001/XMLSchema#string

P478

277

http://www.w3.org/2001/XMLSchema#string

P50

Anton Wellstein

P577

2002-07-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

12122009

http://www.w3.org/2001/XMLSchema#string