Lifespan extension and cancer prevention in HER-2/neu transgenic mice treated with low intermittent doses of rapamycin
about
Inhibition of the Mechanistic Target of Rapamycin (mTOR)-Rapamycin and BeyondA metabolic perspective of Peto's paradox and cancerIdentification of Salvia haenkei as gerosuppressant agent by using an integrated senescence-screening assayLatest progress in tyrosine kinase inhibitorsTarget of rapamycin signalling mediates the lifespan-extending effects of dietary restriction by essential amino acid alteration.From rapalogs to anti-aging formula.Gerosuppression in confluent cells.Targeting tumor-initiating cells: eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction.Polyphenol-rich extract of Pimenta dioica berries (Allspice) kills breast cancer cells by autophagy and delays growth of triple negative breast cancer in athymic mice.Fasting levels of hepatic p-S6 are increased in old miceComparison of rapamycin schedules in mice on high-fat diet.Rejuvenating immunity: "anti-aging drug today" eight years later.Koschei the immortal and anti-aging drugsDual mTORC1/C2 inhibitors suppress cellular geroconversion (a senescence program).Rapamycin: An InhibiTOR of Aging Emerges From the Soil of Easter Island.Age related increase in mTOR activity contributes to the pathological changes in ovarian surface epithelium.Gerosuppression by pan-mTOR inhibitors.Overactive mTOR signaling leads to endometrial hyperplasia in aged women and mice.Aberrant mTOR activation in senescence and aging: A mitochondrial stress response?Novel strategies for anti-aging drug discovery.The dog aging project: translational geroscience in companion animals.Oxidative stress at low levels can induce clustered DNA lesions leading to NHEJ mediated mutations.Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency.While reinforcing cell cycle arrest, rapamycin and Torins suppress senescence in UVA-irradiated fibroblasts.The Role of the Mammalian Target of Rapamycin (mTOR) in Pulmonary Fibrosis.A comprehensive approach to the molecular determinants of lifespan using a Boolean model of geroconversion.A system to identify inhibitors of mTOR signaling using high-resolution growth analysis in Saccharomyces cerevisiae.
P2860
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P2860
Lifespan extension and cancer prevention in HER-2/neu transgenic mice treated with low intermittent doses of rapamycin
description
2014 nî lūn-bûn
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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
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2014年論文
@zh-tw
2014年论文
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name
Lifespan extension and cancer ...... ntermittent doses of rapamycin
@ast
Lifespan extension and cancer ...... ntermittent doses of rapamycin
@en
Lifespan extension and cancer ...... ntermittent doses of rapamycin
@nl
type
label
Lifespan extension and cancer ...... ntermittent doses of rapamycin
@ast
Lifespan extension and cancer ...... ntermittent doses of rapamycin
@en
Lifespan extension and cancer ...... ntermittent doses of rapamycin
@nl
prefLabel
Lifespan extension and cancer ...... ntermittent doses of rapamycin
@ast
Lifespan extension and cancer ...... ntermittent doses of rapamycin
@en
Lifespan extension and cancer ...... ntermittent doses of rapamycin
@nl
P2093
P2860
P3181
P356
P1476
Lifespan extension and cancer ...... ntermittent doses of rapamycin
@en
P2093
Anna V Semenchenko
Irina G Popovich
Margarita L Tyndyk
Maria N Yurova
Mark A Zabezhinski
Vladimir N Anisimov
P2860
P304
P3181
P356
10.4161/CBT.28164
P407
P577
2014-05-01T00:00:00Z