Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse development
about
Dual function of UNC-51-like kinase 3 (Ulk3) in the Sonic hedgehog signaling pathwayCooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapyCentrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesisForward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signalingProtein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tubeLimb anterior-posterior polarity integrates activator and repressor functions of GLI2 as well as GLI3A mutation in the mouse ttc26 gene leads to impaired hedgehog signalingThe primary cilium as a complex signaling centerSmoothened adopts multiple active and inactive conformations capable of trafficking to the primary cilium.Mys protein regulates protein kinase A activity by interacting with regulatory type Ialpha subunit during vertebrate developmentPituitary adenylyl cyclase activating polypeptide inhibits gli1 gene expression and proliferation in primary medulloblastoma derived tumorsphere culturesGenetic analysis of Hedgehog signaling in ventral body wall development and the onset of omphalocele formation.Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors.SUMOylation by Pias1 regulates the activity of the Hedgehog dependent Gli transcription factorsThe cellular and molecular etiology of the craniofacial defects in the avian ciliopathic mutant talpid2.Genetics and development of neural tube defects.Increased proteolytic processing of full-length Gli2 transcription factor reduces the hedgehog pathway activity in vivo.Hedgehog-induced phosphorylation by CK1 sustains the activity of Ci/Gli activatorSonic hedgehog elevates N-myc gene expression in neural stem cells.Association between PKA gene polymorphism and NTDs in high risk Chinese population in ShanxiThe G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastomaThe hedgehog/Gli signaling paradigm in prostate cancerInversion of Sonic hedgehog action on its canonical pathway by electrical activity.An in vivo chemical genetic screen identifies phosphodiesterase 4 as a pharmacological target for hedgehog signaling inhibitionAscl1-induced neuronal differentiation of P19 cells requires expression of a specific inhibitor protein of cyclic AMP-dependent protein kinase.Hedgehog secretion and signal transduction in vertebrates.Small ubiquitin-like Modifier (SUMO) modification inhibits GLI2 protein transcriptional activity in vitro and in vivo.Regulation of Hedgehog signaling by ubiquitination.Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline.Sonic hedgehog through Gli2 and Gli3 is required for the proper development of placental labyrinthMeasuring Gli2 Phosphorylation by Selected Reaction Monitoring Mass Spectrometry.Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development.The relationship between sonic Hedgehog signaling, cilia, and neural tube defectsThe G protein Gαs acts as a tumor suppressor in sonic hedgehog signaling-driven tumorigenesis.Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockadeUnderstanding Mechanisms of GLI-Mediated Transcription during Craniofacial Development and Disease Using the Ciliopathic Mutant, talpid2.The Signaling Pathways Involved in Chondrocyte Differentiation and Hypertrophic DifferentiationActivation of Hedgehog signaling by loss of GNAS causes heterotopic ossification.Suppressor of Fused Chaperones Gli Proteins To Generate Transcriptional Responses to Sonic Hedgehog Signaling.Protein kinase inhibitor SU6668 attenuates positive regulation of Gli proteins in cancer and multipotent progenitor cells.
P2860
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P2860
Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse development
description
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im Februar 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/02/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/02/01)
@nl
наукова стаття, опублікована в лютому 2009
@uk
مقالة علمية (نشرت في فبراير 2009)
@ar
name
Phosphorylation of Gli2 by pro ...... og-regulated mouse development
@ast
Phosphorylation of Gli2 by pro ...... og-regulated mouse development
@en
Phosphorylation of Gli2 by pro ...... og-regulated mouse development
@nl
type
label
Phosphorylation of Gli2 by pro ...... og-regulated mouse development
@ast
Phosphorylation of Gli2 by pro ...... og-regulated mouse development
@en
Phosphorylation of Gli2 by pro ...... og-regulated mouse development
@nl
prefLabel
Phosphorylation of Gli2 by pro ...... og-regulated mouse development
@ast
Phosphorylation of Gli2 by pro ...... og-regulated mouse development
@en
Phosphorylation of Gli2 by pro ...... og-regulated mouse development
@nl
P2093
P2860
P921
P3181
P1476
Phosphorylation of Gli2 by pro ...... og-regulated mouse development
@en
P2093
Baolin Wang
Chengbing Wang
P2860
P304
P3181
P356
10.1016/J.YDBIO.2008.11.009
P407
P577
2009-02-01T00:00:00Z