Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
about
Melanoma: from melanocyte to genetic alterations and clinical optionsp53 activation by knockdown technologiesPremature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signalingGADD45 induction of a G2/M cell cycle checkpointei24, a p53 response gene involved in growth suppression and apoptosisLi-fraumeni syndromeBehavioral alterations associated with apoptosis and down-regulation of presenilin 1 in the brains of p53-deficient micePriorities for development of research methods in occupational cancerThe p53 family member genes are involved in the Notch signal pathwayRole of activating transcription factor 3 (ATF3) in endoplasmic reticulum (ER) stress-induced sensitization of p53-deficient human colon cancer cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis throughIdentification of the retinoic acid-inducible Gprc5a as a new lung tumor suppressor geneUSP4 inhibits p53 through deubiquitinating and stabilizing ARF-BP1Negative regulation of p53 functions by Daxx and the involvement of MDM2Targeted disruption of Ing2 results in defective spermatogenesis and development of soft-tissue sarcomasEndothelial apoptosis in Braf-deficient miceDuplication of ATR inhibits MyoD, induces aneuploidy and eliminates radiation-induced G1 arrestA C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism.Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domainsThe p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/MA human homolog of the Schizosaccharomyces pombe rad9+ checkpoint control geneA novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1Identification of BTG2, an antiproliferative p53-dependent component of the DNA damage cellular response pathwayWip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent mannerp53 regulates Period2 expression and the circadian clockp53 modulation of TFIIH-associated nucleotide excision repair activityHow aneuploidy affects metabolic control and causes cancerSSRP1 functions as a co-activator of the transcriptional activator p63Dlx genes, p63, and ectodermal dysplasias.Germ line transmission of the Cdk4(R24C) mutation facilitates tumorigenesis and escape from cellular senescence.Proteasome-mediated degradation antagonizes critical levels of the apoptosis-inducing C1D protein.Repression of RNA polymerase I transcription by the tumor suppressor p53UV-Induced stabilization of c-fos and other short-lived mRNAsThe C terminus of p53 family proteins is a cell fate determinantFunctional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppressionMDMX: a novel p53-binding protein with some functional properties of MDM2Suppression of tumorigenesis by the p53 target PUMAOncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switchingSIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during agingp53-independent functions of the p19(ARF) tumor suppressorTreacher Collins syndrome: etiology, pathogenesis and prevention
P2860
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P2860
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
description
1992 nî lūn-bûn
@nan
1992 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի մարտին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
@ast
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
@en
type
label
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
@ast
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
@en
prefLabel
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
@ast
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
@en
P2093
P3181
P356
P1433
P1476
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
@en
P2093
Donehower LA
McArthur MJ
Montgomery CA Jr
P2888
P304
P3181
P356
10.1038/356215A0
P407
P577
1992-03-19T00:00:00Z
P5875
P6179
1027559823