Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton.
about
Structural insight into the binding diversity between the Tyr-phosphorylated human ephrinBs and Nck2 SH2 domainPinpointing phosphotyrosine-dependent interactions downstream of the collagen receptor DDR1Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translationIdentification and functional characterization of a novel human misshapen/Nck interacting kinase-related kinase, hMINK betaProtein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAsTargeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasisDissecting Nck/Dock signaling pathways in Drosophila visual system.Actin remodeling by Nck regulates endothelial lumen formationIntegration of linear and dendritic actin nucleation in Nck-induced actin comets.Interaction domains: from simple binding events to complex cellular behaviorMolecular dissection of PINCH-1 reveals a mechanism of coupling and uncoupling of cell shape modulation and survivalThe structure, expression and function prediction of DAZAP2, a down-regulated gene in multiple myelomaA novel role of protein tyrosine kinase2 in mediating chloride secretion in human airway epithelial cellsRegulation of process retraction and cell migration by EphA3 is mediated by the adaptor protein Nck1Nck adaptor proteins control the organization of neuronal circuits important for walking.Nck1 depletion induces activation of the PI3K/Akt pathway by attenuating PTP1B protein expression.Non-overlapping functions of Nck1 and Nck2 adaptor proteins in T cell activation.Coordinated activation of the Rac-GAP β2-chimaerin by an atypical proline-rich domain and diacylglycerol.Dock mediates Scar- and WASp-dependent actin polymerization through interaction with cell adhesion molecules in founder cells and fusion-competent myoblasts.[A uNick protein].Dock/Nck facilitates PTP61F/PTP1B regulation of insulin signalling.Differential regulation of protein tyrosine kinase signaling by Dock and the PTP61F variants.The cytoplasmic adaptor protein Caskin mediates Lar signal transduction during Drosophila motor axon guidance.Nck proteins maintain the adult glomerular filtration barrier.Nck adapter proteins: functional versatility in T cellsNck adapters are involved in the formation of dorsal ruffles, cell migration, and Rho signaling downstream of the platelet-derived growth factor beta receptor.NMR evidence for forming highly populated helical conformations in the partially folded hNck2 SH3 domain.Nckbeta adapter controls neuritogenesis by maintaining the cellular paxillin level.Proteomic analysis of tyrosine phosphorylation during human liver transplantation.Requirement of Nck adaptors for actin dynamics and cell migration stimulated by platelet-derived growth factor B.Tyrosine-phosphorylated SOCS3 interacts with the Nck and Crk-L adapter proteins and regulates Nck activation.The C-terminal domain of Rac1 contains two motifs that control targeting and signaling specificity.The adaptor protein Nck-1 couples the netrin-1 receptor DCC (deleted in colorectal cancer) to the activation of the small GTPase Rac1 through an atypical mechanism.Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion.Cortactin tyrosine phosphorylation requires Rac1 activity and association with the cortical actin cytoskeleton.DOCK5 functions as a key signaling adaptor that links FcεRI signals to microtubule dynamics during mast cell degranulationThe actin-binding protein UNC-115/abLIM controls formation of lamellipodia and filopodia and neuronal morphogenesis in Caenorhabditis elegansA novel interaction between the SH2 domain of signaling adaptor protein Nck-1 and the upstream regulator of the Rho family GTPase Rac1 engulfment and cell motility 1 (ELMO1) promotes Rac1 activation and cell motility.Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-LThe Down syndrome cell adhesion molecule (DSCAM) interacts with and activates Pak.
P2860
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P2860
Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton.
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton.
@ast
Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton.
@en
type
label
Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton.
@ast
Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton.
@en
prefLabel
Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton.
@ast
Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton.
@en
P2093
P2860
P356
P1433
P1476
Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204782
P407
P577
2001-10-01T00:00:00Z
P6179
1013443654