Cluster size regulates protein sorting in the immunological synapse
about
Dynamic Regulation of TCR-Microclusters and the Microsynapse for T Cell ActivationBiophysical Aspects of T Lymphocyte Activation at the Immune SynapseAutoimmune therapies targeting costimulation and emerging trends in multivalent therapeuticsRegulation of T-cell receptor signaling by the actin cytoskeleton and poroelastic cytoplasmDissecting T-cell activation with high-resolution live-cell microscopyImpaired T-Cell Function in B-Cell Lymphoma: A Direct Consequence of Events at the Immunological Synapse?Controversy and consensus regarding myosin II function at the immunological synapseT-cells play the classics with a different spinLigand mobility modulates immunological synapse formation and T cell activationElastohydrodynamics and Kinetics of Protein Patterning in the Immunological SynapseAltered actin centripetal retrograde flow in physically restricted immunological synapsesMyosin IIA modulates T cell receptor transport and CasL phosphorylation during early immunological synapse formationUsing patterned supported lipid membranes to investigate the role of receptor organization in intercellular signaling.Restriction of receptor movement alters cellular response: physical force sensing by EphA2.Actin retrograde flow and actomyosin II arc contraction drive receptor cluster dynamics at the immunological synapse in Jurkat T cells.Characterization of dynamic actin associations with T-cell receptor microclusters in primary T cells.F-actin flow drives affinity maturation and spatial organization of LFA-1 at the immunological synapse.Surface plasmon resonance for high-throughput ligand screening of membrane-bound proteinsSize-based chromatography of signaling clusters in a living cell membraneSingle-molecule spectroscopy and imaging of biomolecules in living cellsSpatial organization of EphA2 at the cell-cell interface modulates trans-endocytosis of ephrinA1.The immunological synapse: a dynamic platform for local signaling.A tethered bilayer assembled on top of immobilized calmodulin to mimic cellular compartmentalization.Engineering supported membranes for cell biology.Roles of the cytoskeleton in regulating EphA2 signals.Multimolecular analysis of stable immunological synapses reveals sustained recruitment and sequential assembly of signaling clustersLigand-mediated friction determines morphodynamics of spreading T cellsAnalysis of molecular diffusion by first-passage time variance identifies the size of confinement zonesT-cell triggering thresholds are modulated by the number of antigen within individual T-cell receptor clusters.Nanofabrication for the analysis and manipulation of membranes.Supported membranes embedded with fixed arrays of gold nanoparticlesCodelivery of antigen and an immune cell adhesion inhibitor is necessary for efficacy of soluble antigen arrays in experimental autoimmune encephalomyelitisEphA2 receptor activation by monomeric Ephrin-A1 on supported membranes.E-cadherin junction formation involves an active kinetic nucleation process.Spatial-temporal reorganization of activated integrins.3D Bayesian cluster analysis of super-resolution data reveals LAT recruitment to the T cell synapse.DNA-mediated assembly of protein heterodimers on membrane surfaces.Patterned two-photon photoactivation illuminates spatial reorganization in live cells.Spatial organization and signal transduction at intercellular junctionsSignaling clusters in the cell membrane.
P2860
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P2860
Cluster size regulates protein sorting in the immunological synapse
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Cluster size regulates protein sorting in the immunological synapse
@ast
Cluster size regulates protein sorting in the immunological synapse
@en
type
label
Cluster size regulates protein sorting in the immunological synapse
@ast
Cluster size regulates protein sorting in the immunological synapse
@en
prefLabel
Cluster size regulates protein sorting in the immunological synapse
@ast
Cluster size regulates protein sorting in the immunological synapse
@en
P2093
P2860
P356
P1476
Cluster size regulates protein sorting in the immunological synapse
@en
P2093
Jay T Groves
Jeffrey A Nye
Niña C Hartman
P2860
P304
12729-12734
P356
10.1073/PNAS.0902621106
P407
P577
2009-07-21T00:00:00Z