Topoisomerase II and histone deacetylase inhibitors delay the G2/M transition by triggering the p38 MAPK checkpoint pathway
about
The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic inventionThe SET and transposase domain protein Metnase enhances chromosome decatenation: regulation by automethylationMetnase mediates resistance to topoisomerase II inhibitors in breast cancer cellsMaintaining Genome Stability in Defiance of Mitotic DNA DamageThe DNA damage response induced by infection with human cytomegalovirus and other virusesPIASgamma is required for faithful chromosome segregation in human cellsPhosphorylation of Hsl1 by Hog1 leads to a G2 arrest essential for cell survival at high osmolarityA mitotic topoisomerase II checkpoint in budding yeast is required for genome stability but acts independently of Pds1/securin.A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity.Brd4 is required for recovery from antimicrotubule drug-induced mitotic arrest: preservation of acetylated chromatinExtracellular signal-regulated kinase 1/2 activity is not required in mammalian cells during late G2 for timely entry into or exit from mitosisDietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpointP38 mitogen-activated protein kinase activity is required during mitosis for timely satisfaction of the mitotic checkpoint but not for the fidelity of chromosome segregation.Effects of conditional depletion of topoisomerase II on cell cycle progression in mammalian cells.A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.DNA topoisomerase II-dependent control of the cell cycle progression in root meristems of Allium cepa.Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogueA new isoquinolinium derivative, Cadein1, preferentially induces apoptosis in p53-defective cancer cells with functional mismatch repair via a p38-dependent pathway.Safeguarding entry into mitosis: the antephase checkpoint.MAPK-activated protein kinase 2 is required for mouse meiotic spindle assembly and kinetochore-microtubule attachment.Mammalian TIMELESS is required for ATM-dependent CHK2 activation and G2/M checkpoint control.Oxidative species and S-glutathionyl conjugates in the apoptosis induction by allyl thiosulfate.Compromised spindle assembly checkpoint due to altered expression of Ubch10 and Cdc20 in human papillomavirus type 16 E6- and E7-expressing keratinocytesThe effects of histone deacetylase inhibitors on heterochromatin: implications for anticancer therapy?Diverse mitotic and interphase functions of condensins in Drosophila.p38α MAPK is a MTOC-associated protein regulating spindle assembly, spindle length and accurate chromosome segregation during mouse oocyte meiotic maturation.Depletion of topoisomerase IIalpha leads to shortening of the metaphase interkinetochore distance and abnormal persistence of PICH-coated anaphase threads.Revised genetic requirements for the decatenation G2 checkpoint: the role of ATM.Adiponectin stimulates proliferation of adult hippocampal neural stem/progenitor cells through activation of p38 mitogen-activated protein kinase (p38MAPK)/glycogen synthase kinase 3β (GSK-3β)/β-catenin signaling cascade.The decatenation checkpoint.Pivotal Role of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 in Inflammatory Pulmonary Diseases.Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression.Phosphorylation of Plk1 at Ser326 regulates its functions during mitotic progressionSUMO modification of DNA topoisomerase II: trying to get a CENse of it allKinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2.Metnase mediates chromosome decatenation in acute leukemia cells.Non-classical p38 map kinase functions: cell cycle checkpoints and survival.Mitosis in vertebrates: the G2/M and M/A transitions and their associated checkpoints.Checkpoint control and cancer.Stressing mitosis to death.
P2860
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P2860
Topoisomerase II and histone deacetylase inhibitors delay the G2/M transition by triggering the p38 MAPK checkpoint pathway
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Topoisomerase II and histone d ...... he p38 MAPK checkpoint pathway
@ast
Topoisomerase II and histone d ...... he p38 MAPK checkpoint pathway
@en
type
label
Topoisomerase II and histone d ...... he p38 MAPK checkpoint pathway
@ast
Topoisomerase II and histone d ...... he p38 MAPK checkpoint pathway
@en
prefLabel
Topoisomerase II and histone d ...... he p38 MAPK checkpoint pathway
@ast
Topoisomerase II and histone d ...... he p38 MAPK checkpoint pathway
@en
P2093
P2860
P356
P1476
Topoisomerase II and histone d ...... he p38 MAPK checkpoint pathway
@en
P2093
Alexei Mikhailov
Conly L Rieder
Mio Shinohara
P2860
P304
P356
10.1083/JCB.200405167
P407
P577
2004-08-09T00:00:00Z