Bisphosphonate inhibition of a Plasmodium farnesyl diphosphate synthase and a general method for predicting cell-based activity from enzyme data
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Lipophilic Bisphosphonates as Dual Farnesyl/Geranylgeranyl Diphosphate Synthase Inhibitors: An X-ray and NMR InvestigationInhibition of Staphyloxanthin Virulence Factor Biosynthesis in Staphylococcus aureus : In Vitro, in Vivo, and Crystallographic Results †Molecular Characterization of a Novel Geranylgeranyl Pyrophosphate Synthase from Plasmodium ParasitesChemo-Immunotherapeutic Antimalarials Targeting Isoprenoid BiosynthesisLipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activitySqualene synthase as a target for Chagas disease therapeuticsDynamic Structure and Inhibition of a Malaria Drug Target: Geranylgeranyl Diphosphate SynthaseChemical Exchange Saturation Transfer (CEST) Agents: Quantum Chemistry and MRI.Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds.Multitarget drug discovery for tuberculosis and other infectious diseases.Lipophilic bisphosphonates are potent inhibitors of Plasmodium liver-stage growth.Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network.In Vitro and In Vivo Investigation of the Inhibition of Trypanosoma brucei Cell Growth by Lipophilic Bisphosphonates.Antibacterial drug leads: DNA and enzyme multitargetingIn Vitro and in Vivo Activity of Multitarget Inhibitors against Trypanosoma bruceiCloning and characterization of bifunctional enzyme farnesyl diphosphate/geranylgeranyl diphosphate synthase from Plasmodium falciparumCharacterization of potential drug targets farnesyl diphosphate synthase and geranylgeranyl diphosphate synthase in Schistosoma mansoni.From crystal to compound: structure-based antimalarial drug discovery.Use of thermal melt curves to assess the quality of enzyme preparationsBacterial Cell Growth Inhibitors Targeting Undecaprenyl Diphosphate Synthase and Undecaprenyl Diphosphate Phosphatase.
P2860
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P2860
Bisphosphonate inhibition of a Plasmodium farnesyl diphosphate synthase and a general method for predicting cell-based activity from enzyme data
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2008 nî lūn-bûn
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2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
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2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年學術文章
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name
Bisphosphonate inhibition of a ...... ased activity from enzyme data
@ast
Bisphosphonate inhibition of a ...... ased activity from enzyme data
@en
type
label
Bisphosphonate inhibition of a ...... ased activity from enzyme data
@ast
Bisphosphonate inhibition of a ...... ased activity from enzyme data
@en
prefLabel
Bisphosphonate inhibition of a ...... ased activity from enzyme data
@ast
Bisphosphonate inhibition of a ...... ased activity from enzyme data
@en
P2093
P2860
P356
P1476
Bisphosphonate inhibition of a ...... ased activity from enzyme data
@en
P2093
Dushyant Mukkamala
Eric Oldfield
Joo Hwan No
Lauren M Cass
Ting-Kai Chang
P2860
P304
P356
10.1021/JM8009074
P407
P577
2008-12-01T00:00:00Z