Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapies
about
Mammalian lipoxygenases and their biological relevanceA high throughput screen identifies potent and selective inhibitors to human epithelial 15-lipoxygenase-2A potent and selective inhibitor targeting human and murine 12/15-LOX.The potential of 12/15-lipoxygenase inhibitors in stroke therapy.Rational Development of a Potent 15-Lipoxygenase-1 Inhibitor with in Vitro and ex Vivo Anti-inflammatory Properties.PPAR-delta promotes survival of breast cancer cells in harsh metabolic conditionsInflammatory responses in brain ischemia.15-Lipoxygenase inhibitors: a patent review.The role of Ca2+ in cell death caused by oxidative glutamate toxicity and ferroptosis.Human 15-LOX-1 active site mutations alter inhibitor binding and decrease potency.Tau-mediated iron export prevents ferroptotic damage after ischemic stroke.12/15-Lipoxygenase Inhibition or Knockout Reduces Warfarin-Associated Hemorrhagic Transformation After Experimental Stroke.Genetic deletion of 12/15 lipoxygenase promotes effective resolution of inflammation following myocardial infarction.Hypoxic cardiac fibroblasts from failing human hearts decrease cardiomyocyte beating frequency in an ALOX15 dependent manner
P2860
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P2860
Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapies
description
2014 nî lūn-bûn
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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
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name
Potent and selective inhibitor ...... enase as anti-stroke therapies
@ast
Potent and selective inhibitor ...... enase as anti-stroke therapies
@en
type
label
Potent and selective inhibitor ...... enase as anti-stroke therapies
@ast
Potent and selective inhibitor ...... enase as anti-stroke therapies
@en
prefLabel
Potent and selective inhibitor ...... enase as anti-stroke therapies
@ast
Potent and selective inhibitor ...... enase as anti-stroke therapies
@en
P2093
P2860
P50
P356
P1476
Potent and selective inhibitor ...... enase as anti-stroke therapies
@en
P2093
David J Maloney
Ganesha Rai
Giovanni Diaz
Joo Eun Jung
Klaus van Leyen
Lena Schultz
Netra Joshi
Qiangli Zhang
Steve Perry
P2860
P304
P356
10.1021/JM401915R
P407
P577
2014-05-13T00:00:00Z