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Rationally designed turn promoting mutation in the amyloid-β peptide sequence stabilizes oligomers in solutionThe amyloid-beta precursor protein: integrating structure with biological functionTargeting the proper amyloid-beta neuronal toxins: a path forward for Alzheimer's disease immunotherapeuticsDiversity, biogenesis and function of microbial amyloidsHydrogen sulfide inhibits amyloid formationThe roles of turn formation and cross-strand interactions in fibrillization of peptides derived from the OspA single-layer beta-sheetStepwise dynamics of epitaxially growing single amyloid fibrils.Spontaneous fibril formation by polyalanines; discontinuous molecular dynamics simulationsEngineering amyloid-like assemblies from unstructured peptides via site-specific lipid conjugationCharacterization of oligomers of heterogeneous size as precursors of amyloid fibril nucleation of an SH3 domain: an experimental kinetics study.Environmental conditions affect the kinetics of nucleation of amyloid fibrils and determine their morphology.Structures of malonic acid diamide/phospholipid composites and their lipoplexes.Molecular architecture of Aβ fibrils grown in cerebrospinal fluid solution and in a cell culture model of Aβ plaque formation.Protein fiber linear dichroism for structure determination and kinetics in a low-volume, low-wavelength couette flow cellEffect of the amyloid β hairpin's structure on the handedness of helices formed by its aggregates.Glycation in Demetalated Superoxide Dismutase 1 Prevents Amyloid Aggregation and Produces Cytotoxic Ages Adducts.Alpha-helix targeting reduces amyloid-beta peptide toxicity.Mirror-image phage display: aiming at the mirror.Mechanism of accelerated assembly of beta-amyloid filaments into fibrils by KLVFFK(6).Models of beta-amyloid ion channels in the membrane suggest that channel formation in the bilayer is a dynamic process.Sequence determinants of enhanced amyloidogenicity of Alzheimer A{beta}42 peptide relative to A{beta}40.Differential post-translational modifications of transthyretin in Alzheimer's disease: a study of the cerebral spinal fluid.Systematic analysis of aggregates from 38 kinds of non disease-related proteins: identifying the intrinsic propensity of polypeptides to form amyloid fibrils.Metal ion-dependent, reversible, protein filament formation by designed beta-roll polypeptides.Albumin fibrillization induces apoptosis via integrin/FAK/Akt pathway.BETASCAN: probable beta-amyloids identified by pairwise probabilistic analysis.Alteration of transthyretin microheterogeneity in serum of multiple trauma patients.Mechanism of docosahexaenoic acid-induced inhibition of in vitro Abeta1-42 fibrillation and Abeta1-42-induced toxicity in SH-S5Y5 cells.Molecular structures of quiescently grown and brain-derived polymorphic fibrils of the Alzheimer amyloid abeta9-40 peptide: a comparison to agitated fibrils.Folding and membrane insertion of amyloid-beta (25-35) peptide and its mutants: implications for aggregation and neurotoxicity.The turn formation at positions 22 and 23 in the 42-mer amyloid beta peptide: the emerging role in the pathogenesis of Alzheimer's disease.Intrinsic linear heterogeneity of amyloid β protein fibrils revealed by higher resolution mass-per-length determinations.Structure-function relationships of pre-fibrillar protein assemblies in Alzheimer's disease and related disordersStatistical analysis and molecular dynamics simulations of ambivalent α-helices.Immune and myodegenerative pathomechanisms in inclusion body myositisComputational backbone mutagenesis of Abeta peptides: probing the role of backbone hydrogen bonds in aggregation.Energy landscape of amyloidogenic peptide oligomerization by parallel-tempering molecular dynamics simulation: significant role of Asn ladder.Molecular dynamics simulations of anti-aggregation effect of ibuprofen.Conformational transition of amyloid beta-peptide.Sulfate anion delays the self-assembly of human insulin by modifying the aggregation pathway.
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Alzheimer's amyloid fibrils: structure and assembly.
@ast
Alzheimer's amyloid fibrils: structure and assembly.
@en
type
label
Alzheimer's amyloid fibrils: structure and assembly.
@ast
Alzheimer's amyloid fibrils: structure and assembly.
@en
prefLabel
Alzheimer's amyloid fibrils: structure and assembly.
@ast
Alzheimer's amyloid fibrils: structure and assembly.
@en
P1476
Alzheimer's amyloid fibrils: structure and assembly.
@en
P2093
L C Serpell
P356
10.1016/S0925-4439(00)00029-6
P407
P577
2000-07-01T00:00:00Z