Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway
about
The therapeutic potential of metal-based antimalarial agents: implications for the mechanism of actionThe genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discoveryArtemisinin, an Endoperoxide Antimalarial, Disrupts the Hemoglobin Catabolism and Heme Detoxification Systems in Malarial ParasitePotencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malariaStructure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparumHemozoin: oil versus waterRecombinant Plasmepsin 1 from the Human Malaria Parasite Plasmodium falciparum : Enzymatic Characterization, Active Site Inhibitor Design, and Structural AnalysisCrystal structures of the free and inhibited forms of plasmepsin I (PMI) from Plasmodium falciparumA Plasmodium falciparum dipeptidyl aminopeptidase I participates in vacuolar hemoglobin degradationExpression and characterization of the Plasmodium falciparum haemoglobinase falcipain-3Separation of Plasmodium falciparum late stage-infected erythrocytes by magnetic meansMetabolic QTL analysis links chloroquine resistance in Plasmodium falciparum to impaired hemoglobin catabolismA role for falcilysin in transit peptide degradation in the Plasmodium falciparum apicoplastIdentification and characterization of falcilysin, a metallopeptidase involved in hemoglobin catabolism within the malaria parasite Plasmodium falciparumFour plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine.Plasmepsin II, an acidic hemoglobinase from the Plasmodium falciparum food vacuole, is active at neutral pH on the host erythrocyte membrane skeleton.Malarial hemozoin: from target to toolMalaria pigment crystals as magnetic micro-rotors: key for high-sensitivity diagnosis.Malaria parasites tolerate a broad range of ionic environments and do not require host cation remodellingProteolytic stability of beta-peptide bonds probed using quenched fluorescent substrates incorporating a hemoglobin cleavage site.Labelling of four distinct trophozoite falcipains of Plasmodium falciparum by a cystatin-derived probe.Active site contribution to specificity of the aspartic proteases plasmepsins I and II.A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug PiperaquineAntimalarial synergy of cysteine and aspartic protease inhibitors.Computational perspectives into plasmepsins structure-function relationship: implications to inhibitors design.New class of small nonpeptidyl compounds blocks Plasmodium falciparum development in vitro by inhibiting plasmepsinsHigh level expression and characterisation of Plasmepsin II, an aspartic proteinase from Plasmodium falciparum.Probing the chloroquine resistance locus of Plasmodium falciparum with a novel class of multidentate metal(III) coordination complexes.Identification and Dynamic Regulation of microRNAs Involved in Salt Stress Responses in Functional Soybean Nodules by High-Throughput SequencingAntimalarial effects of vinyl sulfone cysteine proteinase inhibitors.Structural studies of vacuolar plasmepsinsFunctional expression of falcipain, a Plasmodium falciparum cysteine proteinase, supports its role as a malarial hemoglobinase.Phenotypic reversal of the btn1 defects in yeast by chloroquine: a yeast model for Batten disease.Antimalarial activity enhancement in hydroxymethylcarbonyl (HMC) isostere-based dipeptidomimetics targeting malarial aspartic protease plasmepsin.Trafficking of plasmepsin II to the food vacuole of the malaria parasite Plasmodium falciparum.Inhibition of hemozoin formation in Plasmodium falciparum trophozoite extracts by heme analogs: possible implication in the resistance to malaria conferred by the beta-thalassemia trait.Plasmodium falciparum ookinete expression of plasmepsin VII and plasmepsin X.Proteases of malaria parasites: new targets for chemotherapy.Co-ordinated stage-dependent enhancement of Plasmodium falciparum antioxidant enzymes and heat shock protein expression in parasites growing in oxidatively stressed or G6PD-deficient red blood cells.Structure of malaria pigment and related propanoate-linked metalloporphyrin dimers.
P2860
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P2860
Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway
description
1994 nî lūn-bûn
@nan
1994 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway
@ast
Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway
@en
Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway
@nl
type
label
Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway
@ast
Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway
@en
Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway
@nl
prefLabel
Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway
@ast
Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway
@en
Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway
@nl
P2093
P2860
P356
P1476
Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway
@en
P2093
D E Goldberg
I Y Gluzman
K L Duffin
S E Francis
P2860
P304
P356
10.1172/JCI117140
P407
P577
1994-04-01T00:00:00Z