Sequence and evolution of the human germline V lambda repertoire.
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Frequent N addition and clonal relatedness among immunoglobulin lambda light chains expressed in rheumatoid arthritis synovia and PBL, and the influence of V lambda gene segment utilization on CDR3 lengthPerturbations in the impact of mutational activity on Vlambda genes in systemic lupus erythematosusTertiary structure of human lambda 6 light chainsIsolation of anti-angiogenesis antibodies from a large combinatorial repertoire by colony filter screening.Exegesis: a procedure to improve gene predictions and its use to find immunoglobulin superfamily proteins in the human and mouse genomes.Somatic hypermutation in autoimmune thyroid disease.Efficient construction of a large nonimmune phage antibody library: the production of high-affinity human single-chain antibodies to protein antigensAnalysis of VH gene sequences using two web-based immunogenetics resources gives different results, but the affinity maturation status of chronic lymphocytic leukaemia clones as assessed from either of the resulting data sets has no prognostic signiNeutralizing antibodies of botulinum neurotoxin serotype A screened from a fully synthetic human antibody phage display library.B-cell malignancies as a model for cancer vaccines: from prototype protein to next generation genetic chemokine fusions.Delineating Rearrangements in Single Yeast Artificial Chromosomes by Quantitative DNA Fiber Mapping.A novel synthetic naïve human antibody library allows the isolation of antibodies against a new epitope of oncofetal fibronectin.Repertoire of human antibodies against the polysaccharide capsule of Streptococcus pneumoniae serotype 6B.Functional activities and immunoglobulin variable regions of human and murine monoclonal antibodies specific for the P1.7 PorA protein loop of Neisseria meningitidisCoupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodiesA new method for characterizing replacement rate variation in molecular sequences. Application of the Fourier and wavelet models to Drosophila and mammalian proteins.A fully synthetic human Fab antibody library based on fixed VH/VL framework pairings with favorable biophysical properties.B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemiaSequencing of the human IG light chain loci from a hydatidiform mole BAC library reveals locus-specific signatures of genetic diversitySystematic analysis of sequences of anti-DNA antibodies--relevance to theories of origin and pathogenicity.Molecular expression systems for anti-DNA antibodies--2.Site-directed mutagenesis reveals regions implicated in the stability and fiber formation of human λ3r light chainsp185, an immunodominant epitope, is an autoantigen mimotope.Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936.Establishment of a novel B cell clonality analysis using single-strand conformation polymorphism of immunoglobulin light chain messenger signalsEvolution by the birth-and-death process in multigene families of the vertebrate immune system.Immunoglobulin heavy chain expression shapes the B cell receptor repertoire in human B cell developmentCamelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform.B lymphocytes of xeroderma pigmentosum or Cockayne syndrome patients with inherited defects in nucleotide excision repair are fully capable of somatic hypermutation of immunoglobulin genes.Human autoantibody silencing by immunoglobulin light chainsHuman monoclonal antibodies targeting carbonic anhydrase IX for the molecular imaging of hypoxic regions in solid tumours.Generation and epitope mapping of high-affinity scFv to eukaryotic elongation factor 1A by dual application of phage display.Molecular cloning and expression of the Fabs of human autoantibodies in Escherichia coli. Determination of the heavy or light chain contribution to the anti-DNA/-cardiolipin activity of the Fab.Modifications to canonical structure sequence patterns: analysis for L1 and L3.A method of estimating the numbers of human and mouse T cell receptors for antigen alpha and beta chain V-genes.Induction of light chain replacement in human plasma cells by caffeine is independent from both the upregulation of RAG protein expression and germ line transcription.Simple approach for ranking structure determining residues.Generation, Diversity Determination, and Application to Antibody Selection of a Human Naïve Fab Library.Intrinsic bias and public rearrangements in the human immunoglobulin Vλ light chain repertoire.A human immunoglobulin lambda locus is similarly well expressed in mice and humans.
P2860
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P2860
Sequence and evolution of the human germline V lambda repertoire.
description
1996 nî lūn-bûn
@nan
1996 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
name
Sequence and evolution of the human germline V lambda repertoire.
@ast
Sequence and evolution of the human germline V lambda repertoire.
@en
Sequence and evolution of the human germline V lambda repertoire.
@nl
type
label
Sequence and evolution of the human germline V lambda repertoire.
@ast
Sequence and evolution of the human germline V lambda repertoire.
@en
Sequence and evolution of the human germline V lambda repertoire.
@nl
prefLabel
Sequence and evolution of the human germline V lambda repertoire.
@ast
Sequence and evolution of the human germline V lambda repertoire.
@en
Sequence and evolution of the human germline V lambda repertoire.
@nl
P2093
P356
P1476
Sequence and evolution of the human germline V lambda repertoire.
@en
P2093
Frippiat JP
Ignatovich O
Lefranc MP
Tomlinson IM
Williams SC
P304
P356
10.1006/JMBI.1996.0636
P407
P577
1996-11-01T00:00:00Z