An intracellular threonine of amyloid-β precursor protein mediates synaptic plasticity deficits and memory loss.
about
APP is cleaved by Bace1 in pre-synaptic vesicles and establishes a pre-synaptic interactome, via its intracellular domain, with molecular complexes that regulate pre-synaptic vesicles functionsThe Intersection of NGF/TrkA Signaling and Amyloid Precursor Protein Processing in Alzheimer's Disease NeuropathologyAmyloid-β precursor protein: Multiple fragments, numerous transport routes and mechanismsAPP intracellular domain acts as a transcriptional regulator of miR-663 suppressing neuronal differentiation.NGF controls APP cleavage by downregulating APP phosphorylation at Thr668: relevance for Alzheimer's disease.The ITM2B (BRI2) gene is a target of BCL6 repression: Implications for lymphomas and neurodegenerative diseases.Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and NeurodegenerationLTP and memory impairment caused by extracellular Aβ and Tau oligomers is APP-dependent.
P2860
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P2860
An intracellular threonine of amyloid-β precursor protein mediates synaptic plasticity deficits and memory loss.
description
2013 nî lūn-bûn
@nan
2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
An intracellular threonine of ...... city deficits and memory loss.
@ast
An intracellular threonine of ...... city deficits and memory loss.
@en
An intracellular threonine of ...... city deficits and memory loss.
@nl
type
label
An intracellular threonine of ...... city deficits and memory loss.
@ast
An intracellular threonine of ...... city deficits and memory loss.
@en
An intracellular threonine of ...... city deficits and memory loss.
@nl
prefLabel
An intracellular threonine of ...... city deficits and memory loss.
@ast
An intracellular threonine of ...... city deficits and memory loss.
@en
An intracellular threonine of ...... city deficits and memory loss.
@nl
P2093
P2860
P50
P1433
P1476
An intracellular threonine of ...... city deficits and memory loss.
@en
P2093
Fabrizio Biundo
Franco Lombino
Robert Tamayev
P2860
P304
P356
10.1371/JOURNAL.PONE.0057120
P407
P577
2013-02-22T00:00:00Z