Subcellular localization determines the stability and axon protective capacity of axon survival factor Nmnat2.
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Two for the Price of One: A Neuroprotective Chaperone Kit within NAD Synthase Protein NMNAT2Deletions within its subcellular targeting domain enhance the axon protective capacity of Nmnat2 in vivoA rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degenerationIdentification of palmitoyltransferase and thioesterase enzymes that control the subcellular localization of axon survival factor nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2)Metabolic profiling of alternative NAD biosynthetic routes in mouse tissuesPreserve and protect: maintaining axons within functional circuits.An RNA binding protein promotes axonal integrity in peripheral neurons by destabilizing REST.Axonal transport declines with age in two distinct phases separated by a period of relative stability.Activity-dependent degeneration of axotomized neuromuscular synapses in Wld S mice.Proteomic Profiling in the Brain of CLN1 Disease Model Reveals Affected Functional Modules.NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies.NMNATs, evolutionarily conserved neuronal maintenance factors.Axonal trafficking of NMNAT2 and its roles in axon growth and survival in vivo.MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2.Diversification of NAD biological role: the importance of location.Amyotrophic lateral sclerosis: Problems and prospects.Concepts for regulation of axon integrity by enwrapping glia.Wallerian degeneration: an emerging axon death pathway linking injury and disease.Signaling mechanisms regulating Wallerian degeneration.The neuroimmunology of degeneration and regeneration in the peripheral nervous system.Molecular mechanisms in the initiation phase of Wallerian degeneration.Roles of palmitoylation in axon growth, degeneration and regeneration.Metabolic Vulnerability in the Neurodegenerative Disease Glaucoma.An Atypical SCF-like Ubiquitin Ligase Complex Promotes Wallerian Degeneration through Regulation of Axonal Nmnat2.A Mechanistic Understanding of Axon Degeneration in Chemotherapy-Induced Peripheral Neuropathy.The axon-protective WLD(S) protein partially rescues mitochondrial respiration and glycolysis after axonal injury.KIF1A mediates axonal transport of BACE1 and identification of independently moving cargoes in living SCG neurons.Prevention of vincristine-induced peripheral neuropathy by genetic deletion of SARM1 in mice.An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in
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Subcellular localization determines the stability and axon protective capacity of axon survival factor Nmnat2.
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2013 nî lūn-bûn
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2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Subcellular localization deter ...... f axon survival factor Nmnat2.
@ast
Subcellular localization deter ...... f axon survival factor Nmnat2.
@en
Subcellular localization deter ...... f axon survival factor Nmnat2.
@nl
type
label
Subcellular localization deter ...... f axon survival factor Nmnat2.
@ast
Subcellular localization deter ...... f axon survival factor Nmnat2.
@en
Subcellular localization deter ...... f axon survival factor Nmnat2.
@nl
prefLabel
Subcellular localization deter ...... f axon survival factor Nmnat2.
@ast
Subcellular localization deter ...... f axon survival factor Nmnat2.
@en
Subcellular localization deter ...... f axon survival factor Nmnat2.
@nl
P2093
P2860
P1433
P1476
Subcellular localization deter ...... f axon survival factor Nmnat2.
@en
P2093
Jonathan Gilley
Michael P Coleman
Stefan Milde
P2860
P304
P356
10.1371/JOURNAL.PBIO.1001539
P407
P577
2013-04-16T00:00:00Z