Adaptive mutations producing efficient replication of genotype 1a hepatitis C virus RNA in normal Huh7 cells
about
Human butyrate-induced transcript 1 interacts with hepatitis C virus NS5A and regulates viral replicationHepatitis C virus RNA replication is regulated by FKBP8 and Hsp90A single-amino-acid mutation in hepatitis C virus NS5A disrupting FKBP8 interaction impairs viral replicationHuman VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5BDDX6 (Rck/p54) is required for efficient hepatitis C virus replication but not for internal ribosome entry site-directed translationReplication fitness and NS5B drug sensitivity of diverse hepatitis C virus isolates characterized by using a transient replication assay.Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cellsReplication of a hepatitis C virus replicon clone in mouse cellsCompensatory Mutations in E1, p7, NS2, and NS3 Enhance Yields of Cell Culture-Infectious Intergenotypic Chimeric Hepatitis C VirusAllelic Variation in the Hepatitis C Virus NS4B Protein Dramatically Influences RNA ReplicationThe C Terminus of Hepatitis C Virus NS4A Encodes an Electrostatic Switch That Regulates NS5A Hyperphosphorylation and Viral ReplicationStudying Hepatitis C Virus: Making the Best of a Bad VirusActivity of a Potent Hepatitis C Virus Polymerase Inhibitor in the Chimpanzee ModelNS3 Helicase Domains Involved in Infectious Intracellular Hepatitis C Virus Particle AssemblyDevelopment of Intergenotypic Chimeric Replicons To Determine the Broad-Spectrum Antiviral Activities of Hepatitis C Virus Polymerase InhibitorsA Genetic Interaction between Hepatitis C Virus NS4B and NS3 Is Important for RNA ReplicationSelected Replicon Variants with Low-Level In Vitro Resistance to the Hepatitis C Virus NS5B Polymerase Inhibitor PSI-6130 Lack Cross-Resistance with R1479trans-Complementation of an NS2 Defect in a Late Step in Hepatitis C Virus (HCV) Particle Assembly and MaturationProduction of Infectious Genotype 1b Virus Particles in Cell Culture and Impairment by Replication Enhancing MutationsThe Hepatitis C Virus NS5A Stimulates NS5B During In Vitro RNA Synthesis in a Template Specific MannerImpaired Replication of Hepatitis C Virus Containing Mutations in a Conserved NS5B Retinoblastoma Protein-Binding MotifHepatitis C virus replicons: dinosaurs still in business?The autophagy machinery is required to initiate hepatitis C virus replicationHepatitis C Virus and Antiviral Drug ResistanceProtein kinase R modulates c-Fos and c-Jun signaling to promote proliferation of hepatocellular carcinoma with hepatitis C virus infectionCoordination of Hepatitis C Virus Assembly by Distinct Regulatory Regions in Nonstructural Protein 5AHepatitis C virus genomic RNA dimerization is mediated via a kissing complex intermediate.Engineered toxins "zymoxins" are activated by the HCV NS3 protease by removal of an inhibitory protein domain.Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection.Hepatitis C virus NS5A activates the mammalian target of rapamycin (mTOR) pathway, contributing to cell survival by disrupting the interaction between FK506-binding protein 38 (FKBP38) and mTORPSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replicationmiR-122 does not modulate the elongation phase of hepatitis C virus RNA synthesis in isolated replicase complexes.Removal of hepatitis C virus-infected cells by a zymogenized bacterial toxinRole of Hepatitis C virus core protein in viral-induced mitochondrial dysfunction.Preclinical and Clinical Resistance Profile of EDP-239, a Novel Hepatitis C Virus NS5A Inhibitor.Establishment of infectious HCV virion-producing cells with newly designed full-genome replicon RNAPositive and negative modulation of viral and cellular mRNAs by liver-specific microRNA miR-122.Class A scavenger receptor 1 (MSR1) restricts hepatitis C virus replication by mediating toll-like receptor 3 recognition of viral RNAs produced in neighboring cells.Position-dependent function for a tandem microRNA miR-122-binding site located in the hepatitis C virus RNA genome.Isolation and characterization of highly replicable hepatitis C virus genotype 1a strain HCV-RMT
P2860
Q24305040-64D51CDF-EA15-42B2-BF71-36EBA3FE9BA8Q24306116-211C24A2-B9EE-4690-A99A-A2B098999865Q24307609-286FC2CF-1821-4319-97C2-2B6E5CBCEE9AQ24338324-E3342010-F120-4D22-9CAE-21805F51202CQ24609953-6BE87AE6-FBF8-4EDC-9F8F-17F5A3C0E581Q27469483-8A9FEF0B-11F9-41A6-BFCA-F866CDF97D05Q27473106-061139BD-0725-47F6-9386-C190690BA7AFQ27477595-744F505A-D33C-41A5-93EF-3BCB0BD4B95CQ27478033-FF7629A9-D608-4470-985C-AEBCC05B70DAQ27480358-B80DC369-0CF4-49EF-B922-A52006C2B373Q27481029-7BEB5166-D402-45A5-AA97-11DDAC047F5FQ27481034-7C9B2011-3C13-4B5C-A8DC-3F211131F75CQ27484513-49E8B516-C7FD-4FEF-BE50-801FA66AE483Q27486581-DB7913CB-3E8E-43CE-8ABC-4E54EAEFEF47Q27487022-612AA3E0-7AAF-4D3A-89E4-1163865FF48BQ27487128-3B3D413D-0B0D-42E6-B771-234B4643C5BEQ27487389-C102DD8A-27B5-4106-A361-DA31084386E0Q27488316-B76A6F20-0BE9-418D-9516-AC1F0D20780FQ27488616-DCA7FCE1-31E0-4622-9EA0-7BDBD7BBD332Q27488841-2F9EEA82-FD53-4B96-AFAF-87C39831A06DQ27488885-79624AE7-9BCD-41D9-A27C-AE2A68B085C9Q27488905-0C1D7818-9CD2-4ABE-AB69-EBDEF7C49B14Q27489377-E917A960-9970-4C5A-BA67-8779D911D7B2Q28067295-2278F6A5-BEDF-4963-8A78-B5F6CC34A8D6Q28385007-C6B507D4-C4A3-4D0A-8532-83349834EBF1Q28551959-84A7CAAE-AB73-4536-84D7-331317BB75EBQ33799124-ECC54A91-28C8-43DA-98F6-D8BC8ED90963Q33802605-7D89A92C-B153-44FB-B4FD-D5C5DE67D9F2Q33841892-FAED4522-EE41-48DF-AA7B-BE6DA30AD3A4Q33966987-49E57E9D-BB23-48E3-A685-FB65F26F776EQ34045444-9ED8DED9-3999-4FCF-9C1F-44BF93588FAEQ34126418-F48DC3E0-227D-47C7-A500-1EDF9E839804Q34168690-450C7561-6A24-44D0-88F7-605F98617893Q34267922-27C3ED76-3405-46BD-A7C6-85E08981B94CQ34536770-0D2EA4FA-1D3C-4367-A625-11EB6615096DQ34544777-DC20B299-9231-43C2-94ED-61EB97A85DD4Q34611681-B081A073-28B7-4020-8370-7F4BBD50BB9AQ34743740-07E42B20-A227-4B83-9369-A5106BB93837Q34795106-F6E3D48A-E209-4236-BF67-ADBD6EDAA6C7Q35072828-7F49A6FE-4ACE-4D3A-B5D2-A7C0C29C3872
P2860
Adaptive mutations producing efficient replication of genotype 1a hepatitis C virus RNA in normal Huh7 cells
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Adaptive mutations producing e ...... virus RNA in normal Huh7 cells
@ast
Adaptive mutations producing e ...... virus RNA in normal Huh7 cells
@en
type
label
Adaptive mutations producing e ...... virus RNA in normal Huh7 cells
@ast
Adaptive mutations producing e ...... virus RNA in normal Huh7 cells
@en
prefLabel
Adaptive mutations producing e ...... virus RNA in normal Huh7 cells
@ast
Adaptive mutations producing e ...... virus RNA in normal Huh7 cells
@en
P2860
P1433
P1476
Adaptive mutations producing e ...... virus RNA in normal Huh7 cells
@en
P2093
MinKyung Yi
Stanley M Lemon
P2860
P304
P356
10.1128/JVI.78.15.7904-7915.2004
P407
P577
2004-08-01T00:00:00Z