Differential stimulation of the Na+/H+ exchanger determines chloroquine uptake in Plasmodium falciparum
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The malaria parasite cation ATPase PfATP4 and its role in the mechanism of action of a new arsenal of antimalarial drugsNa(+) regulation in the malaria parasite Plasmodium falciparum involves the cation ATPase PfATP4 and is a target of the spiroindolone antimalarialsMutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistanceMalaria parasites tolerate a broad range of ionic environments and do not require host cation remodellingEvolution of a unique Plasmodium falciparum chloroquine-resistance phenotype in association with pfcrt polymorphism in Papua New Guinea and South AmericaMembrane transport in the malaria-infected erythrocyte.Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparumChloroquine resistance in the malarial parasite, Plasmodium falciparum.A Toxoplasma gondii protein with homology to intracellular type Na⁺/H⁺ exchangers is important for osmoregulation and invasion.Dictyostelium discoideum expresses a malaria chloroquine resistance mechanism upon transfection with mutant, but not wild-type, Plasmodium falciparum transporter PfCRT.Molecular and physiologic basis of quinoline drug resistance in Plasmodium falciparum malariaThe human malaria parasite Plasmodium falciparum is not dependent on host coenzyme A biosynthesis.Construction and validation of a detailed kinetic model of glycolysis in Plasmodium falciparum.Unexpected selections of Plasmodium falciparum polymorphisms in previously treatment-naïve areas after monthly presumptive administration of three different anti-malarial drugs in Liberia 1976-78.H+-coupled pantothenate transport in the intracellular malaria parasite.Enzymes Involved in Pyrophosphate and Calcium Metabolism as Targets for Anti-scuticociliate Chemotherapy.Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparumDifferences in trans-stimulated chloroquine efflux kinetics are linked to PfCRT in Plasmodium falciparum.Quantitative pH measurements in Plasmodium falciparum-infected erythrocytes using pHluorin.Plasmodium falciparum Na+/H+ exchanger activity and quinine resistance.X-ray microanalysis investigation of the changes in Na, K, and hemoglobin concentration in plasmodium falciparum-infected red blood cells.A nonpermeant biotin derivative gains access to the parasitophorous vacuole in Plasmodium falciparum-infected erythrocytes permeabilized with streptolysin O.Quantitative calcium measurements in subcellular compartments of Plasmodium falciparum-infected erythrocytes.Dissecting the components of quinine accumulation in Plasmodium falciparum.Modeling metabolism and stage-specific growth of Plasmodium falciparum HB3 during the intraerythrocytic developmental cycle.Functional state of the plasma membrane Ca2+ pump in Plasmodium falciparum-infected human red blood cells.Illumination of the malaria parasite Plasmodium falciparum alters intracellular pH. Implications for live cell imaging.
P2860
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P2860
Differential stimulation of the Na+/H+ exchanger determines chloroquine uptake in Plasmodium falciparum
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Differential stimulation of th ...... ptake in Plasmodium falciparum
@ast
Differential stimulation of th ...... ptake in Plasmodium falciparum
@en
type
label
Differential stimulation of th ...... ptake in Plasmodium falciparum
@ast
Differential stimulation of th ...... ptake in Plasmodium falciparum
@en
prefLabel
Differential stimulation of th ...... ptake in Plasmodium falciparum
@ast
Differential stimulation of th ...... ptake in Plasmodium falciparum
@en
P2093
P2860
P356
P1476
Differential stimulation of th ...... ptake in Plasmodium falciparum
@en
P2093
C P Sanchez
L Grosse-Wortmann
P2860
P304
P356
10.1083/JCB.140.2.335
P407
P577
1998-01-01T00:00:00Z