Interchangeable SF3B1 inhibitors interfere with pre-mRNA splicing at multiple stages
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Modulating splicing with small molecular inhibitors of the spliceosomeSF3b1 mutations associated with myelodysplastic syndromes alter the fidelity of branchsite selection in yeastJerantinine A induces tumor-specific cell death through modulation of splicing factor 3b subunit 1 (SF3B1)Herboxidiene triggers splicing repression and abiotic stress responses in plants.Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins.Roles of Fe-S proteins: from cofactor synthesis to iron homeostasis to protein synthesis.Design, synthesis and in vitro splicing inhibition of desmethyl and carba-derivatives of herboxidieneTherapeutic targeting of splicing in cancer.An Exercise in Extrapolation: Clinical Management of Atypical CML, MDS/MPN-Unclassifiable, and MDS/MPN-RS-T.Whole-exome sequencing identifies recurrent SF3B1 R625 mutation and comutation of NF1 and KIT in mucosal melanoma.A Challenging Pie to Splice: Drugging the Spliceosome.Molecular basis of differential 3' splice site sensitivity to anti-tumor drugs targeting U2 snRNP.Flow cytometric analysis identifies changes in S and M phases as novel cell cycle alterations induced by the splicing inhibitor isoginkgetin.A triple exon-skipping luciferase reporter assay identifies a new CLK inhibitor pharmacophore.Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity.Splicing Factor 3B Subunit 1 Interacts with HIV Tat and Plays a Role in Viral Transcription and Reactivation from Latency
P2860
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P2860
Interchangeable SF3B1 inhibitors interfere with pre-mRNA splicing at multiple stages
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Interchangeable SF3B1 inhibitors interfere with pre-mRNA splicing at multiple stages
@ast
Interchangeable SF3B1 inhibitors interfere with pre-mRNA splicing at multiple stages
@en
type
label
Interchangeable SF3B1 inhibitors interfere with pre-mRNA splicing at multiple stages
@ast
Interchangeable SF3B1 inhibitors interfere with pre-mRNA splicing at multiple stages
@en
prefLabel
Interchangeable SF3B1 inhibitors interfere with pre-mRNA splicing at multiple stages
@ast
Interchangeable SF3B1 inhibitors interfere with pre-mRNA splicing at multiple stages
@en
P2093
P2860
P356
P1433
P1476
Interchangeable SF3B1 inhibitors interfere with pre-mRNA splicing at multiple stages
@en
P2093
Arun K Ghosh
Beth E Prichard
Kerstin A Effenberger
Melissa S Jurica
Veronica K Urabe
P2860
P304
P356
10.1261/RNA.053108.115
P407
P577
2016-01-07T00:00:00Z