Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration. - sprookjes - yvandenbroek - TriplyDB

Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration.

Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration.

http://www.wikidata.org/entity/Q36570146

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β-cell replacement sources for type 1 diabetes: a focus on pancreatic ductal cells A review on hepatocyte nuclear factor-1beta and tumor Reserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tract The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells Transcription factor regulation of pancreatic organogenesis, differentiation and maturation Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis Adult tissue sources for new β cells.Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity.Human β-cell regeneration: progress, hurdles, and controversy.Aberrant innate immune activation following tissue injury impairs pancreatic regeneration.Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice Development of the endocrine pancreas and novel strategies for β-cell mass restoration and diabetes therapy.Concise reviews: In vitro-produced pancreas organogenesis models in three dimensions: self-organization from few stem cells or progenitors.Sox9: a master regulator of the pancreatic program.Dominant and context-specific control of endodermal organ allocation by Ptf1a.Regeneration and repair of the exocrine pancreas.Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3 The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma Transgenic Expression of a Single Transcription Factor Pdx1 Induces Transdifferentiation of Pancreatic Acinar Cells to Endocrine Cells in Adult Mice.A genetic mouse model for progressive ablation and regeneration of insulin producing beta-cells.Salivary Glands: Stem Cells, Self-duplication, or Both?Involvement of Pancreatic Stellate Cells in Regeneration of Remnant Pancreas after Partial Pancreatectomy.The Chromatin Modifier MSK1/2 Suppresses Endocrine Cell Fates during Mouse Pancreatic Development.Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing β-cells to a δ-like fate and reveals a facultative proliferative capacity in aged β-cells.The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma Intraislet Pancreatic Ducts Can Give Rise to Insulin-Positive Cells.Pdx1 regulates pancreas tubulogenesis and E-cadherin expression.Growth factors and medium hyperglycemia induce Sox9+ ductal cell differentiation into β cells in mice with reversal of diabetes REST represses a subset of the pancreatic endocrine differentiation program.Hyperglycaemia attenuates in vivo reprogramming of pancreatic exocrine cells to beta cells in mice.PNA lectin for purifying mouse acinar cells from the inflamed pancreas.Diabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation in Mice.Cells with surface expression of CD133highCD71low are enriched for tripotent colony-forming progenitor cells in the adult murine pancreas.Direct Reprogramming for Pancreatic Beta-Cells Using Key Developmental Genes Anonymous sources: where do adult β cells come from?How to make a functional β-cell Neurogenin3 activation is not sufficient to direct duct-to-beta cell transdifferentiation in the adult pancreas.Pancreatic duct ligation after almost complete β-cell loss: exocrine regeneration but no evidence of β-cell regeneration Beta Cell Regeneration in Adult Mice: Controversy Over the Involvement of Stem Cells.

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Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration.

http://www.wikidata.org/entity/Q36570146

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Spatiotemporal patterns of mul ...... duced facultative restoration.

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Daniel Boyer

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Eric D Bankaitis

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Fong Cheng Pan

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Harry Heimberg

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Xiaobo Xu

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P2860

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

Generalized lacZ expression with the ROSA26 Cre reporter strain

In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning

SOX9 is required for maintenance of the pancreatic progenitor cell pool

Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex

Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase

Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas

Lack of TCF2/vHNF1 in mice leads to pancreas agenesis

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