Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).
about
CTCF binds the proximal exonic region of hTERT and inhibits its transcription.Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancersTranscription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) GeneThe Interplay of Reactive Oxygen Species, Hypoxia, Inflammation, and Sirtuins in Cancer Initiation and ProgressionBroad targeting of angiogenesis for cancer prevention and therapyEffect of connective tissue growth factor on hypoxia-inducible factor 1alpha degradation and tumor angiogenesisThe hTERT promoter enhances the antitumor activity of an oncolytic adenovirus under a hypoxic microenvironmentHypoxia induces telomerase reverse transcriptase (TERT) gene expression in non-tumor fish tissues in vivo: the marine medaka (Oryzias melastigma) model.Hypoxia reoxygenation induces premature senescence in neonatal SD rat cardiomyocytes.Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia.The HIF-1 hypoxia-inducible factor modulates lifespan in C. elegans.RNAi screen for telomerase reverse transcriptase transcriptional regulators identifies HIF1alpha as critical for telomerase function in murine embryonic stem cellsSoliciting strategies for developing cell-based reference materials to advance mesenchymal stromal cell research and clinical translation.TERT promoter mutations lead to high transcriptional activity under hypoxia and temozolomide treatment and predict poor prognosis in gliomas.Purification and identification of a transcription factor, USF-2, binding to E-box element in the promoter of human telomerase reverse transcriptase (hTERT).RFPL3 and CBP synergistically upregulate hTERT activity and promote lung cancer growthTelomeres and immunological diseases of agingMicroenvironmental regulation of telomerase isoforms in human embryonic stem cellsIncreased placental telomerase mRNA in hypertensive disorders of pregnancyHypoxia-inducible factors, stem cells, and cancerGenome-wide identification and annotation of HIF-1α binding sites in two cell lines using massively parallel sequencing.Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene.Impaired Cell Cycle Regulation in a Natural Equine Model of Asthma.Mitochondrial reactive oxygen species trigger hypoxia-inducible factor-dependent extension of the replicative life span during hypoxiaStroma targeting nuclear imaging and radiopharmaceuticals.Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy.The Role of Hypoxia and Cancer Stem Cells in Renal Cell Carcinoma Pathogenesis.The long and short of it: the role of telomeres in fetal origins of adult disease.Upstream stimulatory factor 2 and hypoxia-inducible factor 2α (HIF2α) cooperatively activate HIF2 target genes during hypoxia.Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1α and VEGF receptorsDevelopment of novel therapeutic strategies that target HIF-1.Telomerase activity in pregnancy complications (Review).Endothelial NOS, estrogen receptor beta, and HIFs cooperate in the activation of a prognostic transcriptional pattern in aggressive human prostate cancerTERT alleviates irradiation-induced late rectal injury by reducing hypoxia-induced ROS levels through the activation of NF-κB and autophagy.Placental pseudo-malignancy from a DNA methylation perspective: unanswered questions and future directions.Hypoxia and senescence: the impact of oxygenation on tumor suppressionHuman telomerase expression regulation.Age related cardiovascular dysfunction and effects of physical activity.The growing complexity of HIF-1α's role in tumorigenesis: DNA repair and beyond.Hypoxia inducible factor pathway inhibitors as anticancer therapeutics.
P2860
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P2860
Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).
@ast
Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).
@en
type
label
Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).
@ast
Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).
@en
prefLabel
Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).
@ast
Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).
@en
P2093
P2860
P1476
Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).
@en
P2093
Hirotaka Nishi
Jerry W Shay
Keiichi Isaka
Masaki Inoue
Satoru Kyo
Toshihide Nakada
P2860
P304
P356
10.1128/MCB.24.13.6076-6083.2004
P407
P577
2004-07-01T00:00:00Z