Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients.
about
LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycleStructural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fissionStructural insights into oligomerization and mitochondrial remodelling of dynamin 1-like proteinNovel therapeutics for Alzheimer's disease: an updateLong range physical cell-to-cell signalling via mitochondria inside membrane nanotubes: a hypothesis.Killing Me Softly: Connotations to Unfolded Protein Response and Oxidative Stress in Alzheimer's DiseaseAlterations in Mitochondrial Quality Control in Alzheimer's DiseaseMolecular and biochemical trajectories from diabetes to Alzheimer's disease: A critical appraisalNovel subcellular localization for α-synuclein: possible functional consequencesMitochondrial abnormalities in Alzheimer's disease: possible targets for therapeutic interventionCalcium channel blockers and Alzheimer's diseaseMitochondrial dysfunction: different routes to Alzheimer's disease therapyNeuronal failure in Alzheimer's disease: a view through the oxidative stress looking-glassHuman wild-type full-length tau accumulation disrupts mitochondrial dynamics and the functions via increasing mitofusins.Parkinson's disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexesSAMM50 Affects Mitochondrial Morphology through the Association of Drp1 in Mammalian CellsTau promotes neurodegeneration via DRP1 mislocalization in vivoMitochondrial fission proteins in peripheral blood lymphocytes are potential biomarkers for Alzheimer's diseaseMitochondrial defects and oxidative stress in Alzheimer disease and Parkinson diseaseMolecular mechanisms mediating mitochondrial dynamics and mitophagy and their functional roles in the cardiovascular systemImpaired balance of mitochondrial fission and fusion in Alzheimer's diseaseMitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseasesAmyloid-beta and mitochondria in aging and Alzheimer's disease: implications for synaptic damage and cognitive declineMitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stressOxidative stress and mitochondrial dysfunction in Alzheimer's disease.Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer's Disease.RyR2-Mediated Ca2+ Release and Mitochondrial ROS Generation Partake in the Synaptic Dysfunction Caused by Amyloid β Peptide Oligomers.Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment.Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease.S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease.Alzheimer's disease: diverse aspects of mitochondrial malfunctioning.Mitochondrial Drugs for Alzheimer Disease.A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease.Mitochondrial dynamics in Alzheimer's disease: opportunities for future treatment strategies.Autophagy in neurodegenerative disorders: pathogenic roles and therapeutic implicationsAdvances with RNA interference in Alzheimer's disease research.Aberrant mitochondrial fission in neurons induced by protein kinase C{delta} under oxidative stress conditions in vivo.Development of Therapeutics That Induce Mitochondrial Biogenesis for the Treatment of Acute and Chronic Degenerative Diseases.Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons.
P2860
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P2860
Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Dynamin-like protein 1 reducti ...... Alzheimer's disease patients.
@ast
Dynamin-like protein 1 reducti ...... Alzheimer's disease patients.
@en
type
label
Dynamin-like protein 1 reducti ...... Alzheimer's disease patients.
@ast
Dynamin-like protein 1 reducti ...... Alzheimer's disease patients.
@en
prefLabel
Dynamin-like protein 1 reducti ...... Alzheimer's disease patients.
@ast
Dynamin-like protein 1 reducti ...... Alzheimer's disease patients.
@en
P2093
P2860
P1476
Dynamin-like protein 1 reducti ...... Alzheimer's disease patients.
@en
P2093
Hisashi Fujioka
Xinglong Wang
P2860
P304
P356
10.2353/AJPATH.2008.071208
P407
P50
P577
2008-07-03T00:00:00Z