about
Cell-cell communication via extracellular membrane vesicles and its role in the immune responseRegulation of nucleocytoplasmic shuttling of Bruton's tyrosine kinase (Btk) through a novel SH3-dependent interaction with ankyrin repeat domain 54 (ANKRD54).Transcriptional signatures of Itk-deficient CD3+, CD4+ and CD8+ T-cellsVav links the T cell antigen receptor to the actin cytoskeleton and T cell activation independently of intrinsic Guanine nucleotide exchange activityT-cell signaling regulated by the Tec family kinase, Itk.E-selectin engages PSGL-1 and CD44 through a common signaling pathway to induce integrin alphaLbeta2-mediated slow leukocyte rolling.Differential roles of IL-2-inducible T cell kinase-mediated TCR signals in tissue-specific localization and maintenance of skin intraepithelial T cells.Lipid signaling in T-cell development and functionItk signals promote neuroinflammation by regulating CD4+ T-cell activation and trafficking.PLZF induces an intravascular surveillance program mediated by long-lived LFA-1-ICAM-1 interactions.DEF6, a novel substrate for the Tec kinase ITK, contains a glutamine-rich aggregation-prone region and forms cytoplasmic granules that co-localize with P-bodies.Requirements for selection of conventional and innate T lymphocyte lineages.Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization.Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/TxkAbl tyrosine kinases in T-cell signalingCD98 activation increases surface expression and clusteringof beta1 integrins in MCF-7 cells through FAK/Src- and cytoskeleton-independent mechanisms.Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinaseConformational snapshots of Tec kinases during signaling.The role of Tec family kinases in the regulation of T-helper-cell differentiation.Bruton's tyrosine kinase--an integral protein of B cell development that also has an essential role in the innate immune system.Structure and function of Tec family kinase Itk.Consequences of two naturally occurring missense mutations in the structure and function of Bruton agammaglobulinemia tyrosine kinase.The lymphoma-associated fusion tyrosine kinase ITK-SYK requires pleckstrin homology domain-mediated membrane localization for activation and cellular transformation.Unique ζ-chain motifs mediate a direct TCR-actin linkage critical for immunological synapse formation and T-cell activation.Impaired T-cell development in the absence of Vav1 and Itk.Molecular dynamic simulation to explore the molecular basis of Btk-PH domain interaction with Ins(1,3,4,5)P4.Molecular modeling studies on series of Btk inhibitors using docking, structure-based 3D-QSAR and molecular dynamics simulation: a combined approach.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Tec kinases, actin, and cell adhesion.
@en
type
label
Tec kinases, actin, and cell adhesion.
@en
prefLabel
Tec kinases, actin, and cell adhesion.
@en
P2093
P2860
P1476
Tec kinases, actin, and cell adhesion.
@en
P2093
Irene C Viorritto
Julie A Readinger
Julio Gomez-Rodriguez
Kristen L Mueller
Pamela L Schwartzberg
Richard A Houghtling
P2860
P356
10.1111/J.1600-065X.2007.00534.X
P577
2007-08-01T00:00:00Z