about
Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFATStructural basis for the inhibition of tyrosine kinase activity of ZAP-70Structural Basis for Activation of ZAP-70 by Phosphorylation of the SH2-Kinase LinkerLAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathwayIntramolecular regulatory switch in ZAP-70: analogy with receptor tyrosine kinases.Acetyl CoA carboxylase in cultured fibroblasts: differential biotin dependence in the two types of biotin-responsive multiple carboxylase deficiency.The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway.Reconstitution of T cell receptor signaling in ZAP-70-deficient cells by retroviral transduction of the ZAP-70 gene.Expression and function of Tec, Itk, and Btk in lymphocytes: evidence for a unique role for TecDNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape.Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases.Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm.Stability of an autoinhibitory interface in the structure of the tyrosine kinase ZAP-70 impacts T cell receptor response.Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1.ZAP-70: an essential kinase in T-cell signalingInhibition of ZAP-70 kinase activity via an analog-sensitive allele blocks T cell receptor and CD28 superagonist signaling.Molecular and genetic insights into T-cell antigen receptor signaling.Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell.Stimulation of the phosphatidylinositol pathway can induce T-cell activation.Differential requirements for ZAP-70 in TCR signaling and T cell development.Biotin transport in the rat central nervous system.Molecular and genetic insights into T cell antigen receptor signal transduction.Biotin Transport in the Rat Central Nervous System
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description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Theresa A Kadlecek
@ast
Theresa A Kadlecek
@en
Theresa A Kadlecek
@es
Theresa A Kadlecek
@sl
type
label
Theresa A Kadlecek
@ast
Theresa A Kadlecek
@en
Theresa A Kadlecek
@es
Theresa A Kadlecek
@sl
prefLabel
Theresa A Kadlecek
@ast
Theresa A Kadlecek
@en
Theresa A Kadlecek
@es
Theresa A Kadlecek
@sl
P106
P21
P31
P496
0000-0002-1020-8169