Molecular analysis of the chromosomal breakpoint and fusion transcripts in the acute lymphoblastic SEM cell line with chromosomal translocation t(4;11).
about
P1343
EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemiaMLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell linesDiagnostic tool for the identification of MLL rearrangements including unknown partner genesThe structure of the human ALL-1/MLL/HRX gene.Breakpoints of t(4;11) translocations in the human MLL and AF4 genes in ALL patients are preferentially clustered outside of high-affinity matrix attachment regions.ML-1 cell line lacks a germline MLL locus.t(4;11) leukemias display addiction to MLL-AF4 but not to AF4-MLLA DNA damage repair mechanism is involved in the origin of chromosomal translocations t(4;11) in primary leukemic cells.Biased distribution of chromosomal breakpoints involving the MLL gene in infants versus children and adults with t(4;11) ALL.A highly specific and sensitive fluorescence in situ hybridization assay for the detection of t(4;11)(q21;q23) and concurrent submicroscopic deletions in acute leukaemias.MLL-mediated transcriptional gene regulation investigated by gene expression profiling.
P2860
Q24564948-1A00FE3C-59F8-4E9A-80CE-6A7390293648Q28142772-ED03B17D-C68E-43E7-9D1D-9232996F7415Q33723050-6B1F7255-F832-42F3-BB50-2FB7C72DDFA0Q34457614-E0D0D657-5A25-4170-8E77-03FC9B027460Q38497781-608F567B-1A0D-4AEA-8B4C-569360A75870Q41187786-7E806B96-77A5-4BA8-B33D-E7B71B309EA7Q41498699-055B69B6-9E7F-4E3D-BB30-435F6ABB16BFQ47933583-3AF2B89A-42AC-4BC1-94C0-B03FB3F0F5DAQ48357439-AFAB8ACA-2C05-473D-B00F-6B2E6C5BDC78Q50760326-3B5E6A83-A10A-4CF8-9541-58D174568CEBQ52550858-325EF903-EBF4-43F2-B16F-8244D3576BEA
P2860
Molecular analysis of the chromosomal breakpoint and fusion transcripts in the acute lymphoblastic SEM cell line with chromosomal translocation t(4;11).
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Molecular analysis of the chro ...... mosomal translocation t(4;11).
@en
type
label
Molecular analysis of the chro ...... mosomal translocation t(4;11).
@en
prefLabel
Molecular analysis of the chro ...... mosomal translocation t(4;11).
@en
P2093
P2860
P1476
Molecular analysis of the chro ...... mosomal translocation t(4;11).
@en
P2093
Zweckbronner I
P2860
P304
P356
10.1111/J.1365-2141.1995.TB05151.X
P407
P4510
P577
1995-06-01T00:00:00Z