Discovery and SAR of a novel series of non-MPEP site mGlu₅ PAMs based on an aryl glycine sulfonamide scaffold.

Discovery and SAR of a novel series of non-MPEP site mGlu₅ PAMs based on an aryl glycine sulfonamide scaffold.

Item
http://www.wikidata.org/entity/Q41820126
N-aryl piperazine metabotropic glutamate receptor 5 positive allosteric modulators possess efficacy in preclinical models of NMDA hypofunction and cognitive enhancement.Tetrahydronaphthyridine and dihydronaphthyridinone ethers as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu₅).Molecular Insights into Metabotropic Glutamate Receptor Allosteric ModulationAllosteric modulators for the treatment of schizophrenia: targeting glutamatergic networksRethinking metabotropic glutamate receptor 5 pathological findings in psychiatric disorders: implications for the future of novel therapeutics.mGluR5: exploration of orthosteric and allosteric ligand binding pockets and their applications to drug discovery.Development of 1H-Pyrazolo[3,4-b]pyridines as Metabotropic Glutamate Receptor 5 Positive Allosteric Modulators.
P2860

Discovery and SAR of a novel series of non-MPEP site mGlu₅ PAMs based on an aryl glycine sulfonamide scaffold.

Item
http://www.wikidata.org/entity/Q41820126
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Discovery and SAR of a novel s ...... glycine sulfonamide scaffold.
@en
type
label
Discovery and SAR of a novel s ...... glycine sulfonamide scaffold.
@en
prefLabel
Discovery and SAR of a novel s ...... glycine sulfonamide scaffold.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Discovery and SAR of a novel s ...... glycine sulfonamide scaffold.
@en
P2093
P2860
P304
P31
P356
10.1016/J.BMCL.2012.10.068
P407
P433
P478
P50
P577
P698
P932