Constitutive activation of Stat3alpha in brain tumors: localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2).
about
Apoptosis induced by knockdown of uPAR and MMP-9 is mediated by inactivation of EGFR/STAT3 signaling in medulloblastomaLoss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expressionGlioma-associated cytomegalovirus mediates subversion of the monocyte lineage to a tumor propagating phenotypeSTAT3 inhibits the degradation of HIF-1alpha by pVHL-mediated ubiquitinationIdentification of a PTEN-regulated STAT3 brain tumor suppressor pathwayRadioresistance of Brain TumorsSTAT3 oligonucleotide inhibits tumor angiogenesis in preclinical models of squamous cell carcinomaSTAT6 expression in glioblastoma promotes invasive growthAnti-proliferative activity of the quassinoid NBT-272 in childhood medulloblastoma cellsConstitutive activation of signal transducer and activator of transcription 3 regulates expression of vascular endothelial growth factor in human meningioma differentiation.Down-regulation of GRIM-19 expression is associated with hyperactivation of STAT3-induced gene expression and tumor growth in human cervical cancers.Efficient inhibition of intraperitoneal ovarian cancer growth in nude mice by liposomal delivery of short hairpin RNA against STAT3.Construction of a novel constitutively active chimeric EGFR to identify new targets for therapyProfiling the global tyrosine phosphorylation state.Dysregulated Sonic hedgehog signaling and medulloblastoma consequent to IFN-alpha-stimulated STAT2-independent production of IFN-gamma in the brain.Stat3 orchestrates interaction between endothelial and tumor cells and inhibition of Stat3 suppresses brain metastasis of breast cancer cells.STAT proteins as novel targets for cancer drug discovery.CD133+ brain tumor-initiating cells are dependent on STAT3 signaling to drive medulloblastoma recurrence.A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivoInhibition of STAT3 expression and signaling in resveratrol-differentiated medulloblastoma cells.Vascular endothelial growth factor in eye disease.Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas.FoxM1B transcriptionally regulates vascular endothelial growth factor expression and promotes the angiogenesis and growth of glioma cellsPP2A inhibition with LB100 enhances cisplatin cytotoxicity and overcomes cisplatin resistance in medulloblastoma cells.STAT3 as a target for inducing apoptosis in solid and hematological tumorsSignal transducer and activator of transcription-3: a molecular hub for signaling pathways in gliomasNF-kappaB and STAT3 signaling in glioma: targets for future therapiesSTAT3 regulation of glioblastoma pathogenesis.Tannic acid inhibits EGFR/STAT1/3 and enhances p38/STAT1 signalling axis in breast cancer cells.STATus and Context within the Mammalian Nervous System.The molecular profile of microglia under the influence of glioma.The role of microglia and matrix metalloproteinases involvement in neuroinflammation and gliomasSTAT3 Activation in Glioblastoma: Biochemical and Therapeutic Implications.Role of STAT3 in Genesis and Progression of Human Malignant Gliomas.The Process and Regulatory Components of Inflammation in Brain Oncogenesis.Intronic microRNA suppresses endothelial nitric oxide synthase expression and endothelial cell proliferation via inhibition of STAT3 signaling.SR16388: a steroidal antiangiogenic agent with potent inhibitory effect on tumor growth in vivo.Cell-cell contacts induce STAT3 activity in colon carcinoma cells through an autocrine stimulation loop.Sunitinib induces apoptosis and growth arrest of medulloblastoma tumor cells by inhibiting STAT3 and AKT signaling pathways.Constitutively activated STAT3 frequently coexpresses with epidermal growth factor receptor in high-grade gliomas and targeting STAT3 sensitizes them to Iressa and alkylators
P2860
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P2860
Constitutive activation of Stat3alpha in brain tumors: localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2).
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Constitutive activation of Sta ...... ine kinase receptor (VEGFR-2).
@en
Constitutive activation of Sta ...... elial tyrosine kinase receptor
@nl
type
label
Constitutive activation of Sta ...... ine kinase receptor (VEGFR-2).
@en
Constitutive activation of Sta ...... elial tyrosine kinase receptor
@nl
prefLabel
Constitutive activation of Sta ...... ine kinase receptor (VEGFR-2).
@en
Constitutive activation of Sta ...... elial tyrosine kinase receptor
@nl
P2093
P2860
P356
P1433
P1476
Constitutive activation of Sta ...... ine kinase receptor (VEGFR-2).
@en
P2093
Gregory N Fuller
Laura K Schaefer
Timothy S Schaefer
Zhiyong Ren
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205263
P407
P577
2002-03-01T00:00:00Z
P5875
P6179
1044698881