Dll4, a novel Notch ligand expressed in arterial endothelium
about
Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interactionRegulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesisEgfl7, a novel epidermal growth factor-domain gene expressed in endothelial cellsHERP, a new primary target of Notch regulated by ligand bindingNeurovascular signals suggest a propagation mechanism for endogenous stem cell activation along blood vesselsMembers of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signalingDelta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sproutingIs there a role for Notch signalling in human breast cancer?DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport.Bone Marrow Blood Vessels: Normal and Neoplastic NicheThe role of notch in the cardiovascular system: potential adverse effects of investigational notch inhibitorsHaploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutantsVascular patterning defects associated with expression of activated Notch4 in embryonic endotheliumContext-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In VivoOverexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryosThe divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligandsThe Notch target genes Hey1 and Hey2 are required for embryonic vascular developmentDosage-sensitive requirement for mouse Dll4 in artery developmentNotch signaling is essential for vascular morphogenesis in miceNotch1-Dll4 signalling and mechanical force regulate leader cell formation during collective cell migration.Novel subdomains of the mouse olfactory bulb defined by molecular heterogeneity in the nascent external plexiform and glomerular layers.A novel method of differential gene expression analysis using multiple cDNA libraries applied to the identification of tumour endothelial genes.Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli.Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.Testosterone levels influence mouse fetal Leydig cell progenitors through notch signaling.RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal developmentDll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models.Influence of Dll4 via HIF-1α-VEGF signaling on the angiogenesis of choroidal neovascularization under hypoxic conditions.Bmx tyrosine kinase has a redundant function downstream of angiopoietin and vascular endothelial growth factor receptors in arterial endothelium.The functional role of Notch signaling in human gliomas.Low-dosage inhibition of Dll4 signaling promotes wound healing by inducing functional neo-angiogenesisActivated Notch4 inhibits angiogenesis: role of beta 1-integrin activation.Notch inhibitors for cancer treatment.Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages.The role of dendritic cells in tissue-specific autoimmunity.Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function.Context- and cell-dependent effects of Delta-like 4 targeting in the bone marrow microenvironment.Delta-like ligand 4-Notch signaling regulates bone marrow-derived pericyte/vascular smooth muscle cell formationDevelopmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factorsEthanol stimulates endothelial cell angiogenic activity via a Notch- and angiopoietin-1-dependent pathway.
P2860
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P2860
Dll4, a novel Notch ligand expressed in arterial endothelium
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2000 թվականի հունիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
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name
Dll4, a novel Notch ligand expressed in arterial endothelium
@ast
Dll4, a novel Notch ligand expressed in arterial endothelium
@en
Dll4, a novel Notch ligand expressed in arterial endothelium
@en-gb
Dll4, a novel Notch ligand expressed in arterial endothelium
@nl
type
label
Dll4, a novel Notch ligand expressed in arterial endothelium
@ast
Dll4, a novel Notch ligand expressed in arterial endothelium
@en
Dll4, a novel Notch ligand expressed in arterial endothelium
@en-gb
Dll4, a novel Notch ligand expressed in arterial endothelium
@nl
prefLabel
Dll4, a novel Notch ligand expressed in arterial endothelium
@ast
Dll4, a novel Notch ligand expressed in arterial endothelium
@en
Dll4, a novel Notch ligand expressed in arterial endothelium
@en-gb
Dll4, a novel Notch ligand expressed in arterial endothelium
@nl
P2093
P2860
P921
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Dll4, a novel Notch ligand expressed in arterial endothelium
@en
P2093
C R Kintner
G A Deblandre
J Kitajewski
J R Shutter
W G Richards
P2860
P304
P3181
P407
P577
2000-06-01T00:00:00Z