GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit
about
Identification and characterization of SNX15, a novel sorting nexin involved in protein traffickingIdentification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activationUse of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasisIdentification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gammaHierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptorAcetylcholine muscarinic m1 receptor regulation of cyclic AMP synthesis controls growth factor stimulation of Raf activityIdentification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinasesThe 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase SypTwo signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptorIn vivo binding properties of SH2 domains from GTPase-activating protein and phosphatidylinositol 3-kinaseConstruction of an SH2 domain-binding site with mixed specificityThymocyte activation induces the association of the proto-oncoprotein c-cbl and ras GTPase-activating protein with CD5Interaction of the p85 subunit of PI 3-kinase and its N-terminal SH2 domain with a PDGF receptor phosphorylation site: structural features and analysis of conformational changesJuxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cellsGrb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesisProtein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to RasThe SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptorsMapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector molecules phospholipase C-gamma 2, microtubule-associated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kPhosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinaseCloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85Heregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 co-receptorThe platelet-derived growth factor beta receptor triggers multiple cytoplasmic signaling cascades that arrive at the nucleus as distinguishable inputsIdentification of regions of the Wiskott-Aldrich syndrome protein responsible for association with selected Src homology 3 domainsSpecific binding of Fyn and phosphatidylinositol 3-kinase to the B cell surface glycoprotein CD19 through their src homology 2 domainsDirect association of Grb2 with the p85 subunit of phosphatidylinositol 3-kinaseThe catalytic subunit of phosphatidylinositol 3-kinase is a substrate for the activated platelet-derived growth factor receptor, but not for middle-T antigen-pp60c-src complexesSequence requirements for binding of Src family tyrosine kinases to activated growth factor receptorsMutation of Tyr697, a GRB2-binding site, and Tyr721, a PI 3-kinase binding site, abrogates signal transduction by the murine CSF-1 receptor expressed in Rat-2 fibroblastsIndependent SH2-binding sites mediate interaction of Dok-related protein with RasGTPase-activating protein and NckPlatelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell typesSrc family kinases are required for integrin but not PDGFR signal transduction.Nck adapters are involved in the formation of dorsal ruffles, cell migration, and Rho signaling downstream of the platelet-derived growth factor beta receptor.A nuclear SH3 domain-binding protein that colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks.A 31-amino-acid N-terminal extension regulates c-Crk binding to tyrosine-phosphorylated proteins.The v-Src SH3 domain binds phosphatidylinositol 3'-kinase.Tyrosine 807 of the v-Fms oncogene product controls cell morphology and association with p120RasGAP.A function for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in fibroblasts during mitogenesis: requirement for insulin- and lysophosphatidic acid-mediated signal transduction.Wortmannin blocks lipid and protein kinase activities associated with PI 3-kinase and inhibits a subset of responses induced by Fc epsilon R1 cross-linking.RasGAP Promotes Autophagy and Thereby Suppresses Platelet-Derived Growth Factor Receptor-Mediated Signaling Events, Cellular Responses, and Pathology.Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms.
P2860
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P2860
GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit
description
1992 nî lūn-bûn
@nan
1992 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
GTPase-activating protein and ...... h factor receptor beta subunit
@ast
GTPase-activating protein and ...... h factor receptor beta subunit
@en
GTPase-activating protein and ...... h factor receptor beta subunit
@en-gb
GTPase-activating protein and ...... h factor receptor beta subunit
@nl
type
label
GTPase-activating protein and ...... h factor receptor beta subunit
@ast
GTPase-activating protein and ...... h factor receptor beta subunit
@en
GTPase-activating protein and ...... h factor receptor beta subunit
@en-gb
GTPase-activating protein and ...... h factor receptor beta subunit
@nl
prefLabel
GTPase-activating protein and ...... h factor receptor beta subunit
@ast
GTPase-activating protein and ...... h factor receptor beta subunit
@en
GTPase-activating protein and ...... h factor receptor beta subunit
@en-gb
GTPase-activating protein and ...... h factor receptor beta subunit
@nl
P2093
P2860
P356
P1476
GTPase-activating protein and ...... h factor receptor beta subunit
@en
P2093
A Kashishian
A Kazlauskas
J A Cooper
P2860
P304
P356
10.1128/MCB.12.6.2534
P407
P577
1992-06-01T00:00:00Z