The Cdc42/Rac interactive binding region motif of the Wiskott Aldrich syndrome protein (WASP) is necessary but not sufficient for tight binding to Cdc42 and structure formation
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Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' proteinStructure of the small G protein Cdc42 bound to the GTPase-binding domain of ACKCdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylationProtein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein (WASP)/neuronal WASPThe Wiskott-Aldrich syndromeAutoinhibition regulates cellular localization and actin assembly activity of the diaphanous-related formins FRLalpha and mDia1.Nucleotide binding to the G12V-mutant of Cdc42 investigated by X-ray diffraction and fluorescence spectroscopy: Two different nucleotide states in one crystalControl of mitotic exit in budding yeast. In vitro regulation of Tem1 GTPase by Bub2 and Bfa1.Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.Specific association of nitric oxide synthase-2 with Rac isoforms in activated murine macrophagesPAK6 targets to cell-cell adhesions through its N-terminus in a Cdc42-dependent manner to drive epithelial colony escapeRho GTPases and their effector proteinsInvestigation of the Interaction between Cdc42 and Its Effector TOCA1: HANDOVER OF Cdc42 TO THE ACTIN REGULATOR N-WASP IS FACILITATED BY DIFFERENTIAL BINDING AFFINITIES.Development of a fluorogenic sensor for activated Cdc42.Hierarchical effector protein transport by the Salmonella Typhimurium SPI-1 type III secretion system.Specific patterns of Cdc42 activity are related to distinct elements of T cell polarizationRatiometric Imaging Using a Single Dye Enables Simultaneous Visualization of Rac1 and Cdc42 Activation.Single-molecule dynamics reveals cooperative binding-folding in protein recognitionSopE and SopE2 from Salmonella typhimurium activate different sets of RhoGTPases of the host cell.Regulation of actin polymerization by Arp2/3 complex and WASp/Scar proteins.Slow, reversible, coupled folding and binding of the spectrin tetramerization domain.Biochemical analysis of SopE from Salmonella typhimurium, a highly efficient guanosine nucleotide exchange factor for RhoGTPases.Amino acids of the bacterial toxin SopE involved in G nucleotide exchange on Cdc42.Environment-sensing merocyanine dyes for live cell imaging applicationsWASp in immune-system organization and function.Evidence for two CRIB domains in phospholipase D2 (PLD2) that the enzyme uses to specifically bind to the small GTPase Rac2.Changes in actin dynamics at the T-cell/APC interface: implications for T-cell anergy?The Wiskott-Aldrich syndrome protein: forging the link between actin and cell activation.Rate constants and mechanisms of intrinsically disordered proteins binding to structured targetsCdc42 in actin dynamics: An ordered pathway governed by complex equilibria and directional effector handover.p21-activated kinase 1 plays a critical role in cellular activation by Nef.Conformational switch and role of phosphorylation in PAK activationA Burkholderia pseudomallei type III secreted protein, BopE, facilitates bacterial invasion of epithelial cells and exhibits guanine nucleotide exchange factor activity.Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia.Enterohaemorrhagic and enteropathogenic Escherichia coli use different mechanisms for actin pedestal formation that converge on N-WASP.Tumor-related alternatively spliced Rac1b is not regulated by Rho-GDP dissociation inhibitors and exhibits selective downstream signaling.IL-4 regulation of IL-6 production involves Rac/Cdc42- and p38 MAPK-dependent pathways in keratinocytes.Involvement of small GTPases in Mycoplasma fermentans membrane lipoproteins-mediated activation of macrophages.The role of Cdc42 and Gic1 in the regulation of septin filament formation and dissociationIpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells.
P2860
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P2860
The Cdc42/Rac interactive binding region motif of the Wiskott Aldrich syndrome protein (WASP) is necessary but not sufficient for tight binding to Cdc42 and structure formation
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The Cdc42/Rac interactive bind ...... Cdc42 and structure formation
@ast
The Cdc42/Rac interactive bind ...... Cdc42 and structure formation
@en
The Cdc42/Rac interactive bind ...... Cdc42 and structure formation
@en-gb
The Cdc42/Rac interactive bind ...... Cdc42 and structure formation
@nl
type
label
The Cdc42/Rac interactive bind ...... Cdc42 and structure formation
@ast
The Cdc42/Rac interactive bind ...... Cdc42 and structure formation
@en
The Cdc42/Rac interactive bind ...... Cdc42 and structure formation
@en-gb
The Cdc42/Rac interactive bind ...... Cdc42 and structure formation
@nl
prefLabel
The Cdc42/Rac interactive bind ...... Cdc42 and structure formation
@ast
The Cdc42/Rac interactive bind ...... Cdc42 and structure formation
@en
The Cdc42/Rac interactive bind ...... Cdc42 and structure formation
@en-gb
The Cdc42/Rac interactive bind ...... Cdc42 and structure formation
@nl
P2093
P2860
P3181
P356
P1476
The Cdc42/Rac interactive bind ...... Cdc42 and structure formation
@en
P2093
A Wittinghofer
I R Vetter
J Kuhlmann
M G Rudolph
P2860
P304
18067-18076
P3181
P356
10.1074/JBC.273.29.18067
P407
P50
P577
1998-07-01T00:00:00Z