Human cyclin-dependent kinase-activating kinase exists in three distinct complexes
about
Distinct regions of MAT1 regulate cdk7 kinase and TFIIH transcription activitiesStrong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosomeA yeast four-hybrid system identifies Cdk-activating kinase as a regulator of the XPD helicase, a subunit of transcription factor IIHSubstrate specificity of the cdk-activating kinase (CAK) is altered upon association with TFIIHPurification of a Tat-associated kinase reveals a TFIIH complex that modulates HIV-1 transcriptionThe HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase IINucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAKThe human immunodeficiency virus transactivator Tat interacts with the RNA polymerase II holoenzymeDrosophila Xpd regulates Cdk7 localization, mitotic kinase activity, spindle dynamics, and chromosome segregationSolution structure of the N-terminal domain of the human TFIIH MAT1 subunit: new insights into the RING finger familyCrystal Structure of the FeS Cluster–Containing Nucleotide Excision Repair Helicase XPDKin28 is found within TFIIH and a Kin28-Ccl1-Tfb3 trimer complex with differential sensitivities to T-loop phosphorylation.Mutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit of TFIIHSpecificity of Cdk activation in vivo by the two Caks Mcs6 and Csk1 in fission yeast.RNA antisense abrogation of MAT1 induces G1 phase arrest and triggers apoptosis in aortic smooth muscle cellsExpression of second messenger- and cyclin-dependent protein kinases during postnatal development of rat heartAssembly, subunit composition, and footprint of human DNA repair excision nuclease.The RNA polymerase II general transcription factors: past, present, and future.Ten years of TFIIH.Accessing DNA damage in chromatin: insights from transcription.Functional analysis of the Cdk7.cyclin H.Mat1 complex in mouse embryonic stem cells and embryosRegulation of CDK7 substrate specificity by MAT1 and TFIIH.Mutations in XPB and XPD helicases found in xeroderma pigmentosum patients impair the transcription function of TFIIH.Premature aging and cancer in nucleotide excision repair-disorders.T-loop phosphorylation stabilizes the CDK7-cyclin H-MAT1 complex in vivo and regulates its CTD kinase activityOn the traces of XPD: cell cycle matters - untangling the genotype-phenotype relationship of XPD mutationsTargeting transcription regulation in cancer with a covalent CDK7 inhibitorThe history and future of targeting cyclin-dependent kinases in cancer therapy.CDK7-dependent transcriptional addiction in triple-negative breast cancer.TFIIH subunit alterations causing xeroderma pigmentosum and trichothiodystrophy specifically disturb several steps during transcription.The molecular mechanism of mitotic inhibition of TFIIH is mediated by phosphorylation of CDK7.Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells.Accurate positioning of RNA polymerase II on a natural TATA-less promoter is independent of TATA-binding-protein-associated factors and initiator-binding proteins.Regulation of estrogen receptor transcriptional enhancement by the cyclin A/Cdk2 complex.Multiple CDK inhibitor dinaciclib suppresses neuroblastoma growth via inhibiting CDK2 and CDK9 activityThe lost intrinsic fragmentation of MAT1 protein during granulopoiesis promotes the growth and metastasis of leukemic myeloblasts.Inhibition of cyclin dependent kinase 9 by dinaciclib suppresses cyclin B1 expression and tumor growth in triple negative breast cancerClinical Management of Potential Toxicities and Drug Interactions Related to Cyclin-Dependent Kinase 4/6 Inhibitors in Breast Cancer: Practical Considerations and Recommendations.MAT1-modulated CAK activity regulates cell cycle G(1) exit.Adenovirus type 12-induced fragility of the human RNU2 locus requires p53 function.
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P2860
Human cyclin-dependent kinase-activating kinase exists in three distinct complexes
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Human cyclin-dependent kinase-activating kinase exists in three distinct complexes
@ast
Human cyclin-dependent kinase-activating kinase exists in three distinct complexes
@en
Human cyclin-dependent kinase-activating kinase exists in three distinct complexes
@en-gb
Human cyclin-dependent kinase-activating kinase exists in three distinct complexes
@nl
type
label
Human cyclin-dependent kinase-activating kinase exists in three distinct complexes
@ast
Human cyclin-dependent kinase-activating kinase exists in three distinct complexes
@en
Human cyclin-dependent kinase-activating kinase exists in three distinct complexes
@en-gb
Human cyclin-dependent kinase-activating kinase exists in three distinct complexes
@nl
prefLabel
Human cyclin-dependent kinase-activating kinase exists in three distinct complexes
@ast
Human cyclin-dependent kinase-activating kinase exists in three distinct complexes
@en
Human cyclin-dependent kinase-activating kinase exists in three distinct complexes
@en-gb
Human cyclin-dependent kinase-activating kinase exists in three distinct complexes
@nl
P2093
P2860
P921
P3181
P356
P1476
Human cyclin-dependent kinase-activating kinase exists in three distinct complexes
@en
P2093
P2860
P304
P3181
P356
10.1073/PNAS.93.13.6488
P407
P577
1996-06-01T00:00:00Z