Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase
about
Scrib regulates PAK activity during the cell migration processDok-R plays a pivotal role in angiopoietin-1-dependent cell migration through recruitment and activation of Pak.Essential role for Rac in heregulin beta1 mitogenic signaling: a mechanism that involves epidermal growth factor receptor and is independent of ErbB4.Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling.Epidermal growth factor mediates detachment from and invasion through collagen I and Matrigel in Capan-1 pancreatic cancer cellsp21-activated kinase signaling in breast cancerNeuregulin as a heart failure therapy and mediator of reverse remodelingRegulation of Xenopus gastrulation by ErbB signaling.ErbB2-dependent chemotaxis requires microtubule capture and stabilization coordinated by distinct signaling pathways.FRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated SchwannomasRAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasionA tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteinsInhibition of EGFR-mediated phosphoinositide-3-OH kinase (PI3-K) signaling and glioblastoma phenotype by signal-regulatory proteins (SIRPs)Essential functions of p21-activated kinase 1 in morphogenesis and differentiation of mammary glandsEstrogen regulation of Pak1 and FKHR pathways in breast cancer cellsP21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epitheliumExpression and transactivating functions of the bZIP transcription factor GADD153 in mammary epithelial cellsp21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cellsErbB-beta-catenin complexes are associated with human infiltrating ductal breast and murine mammary tumor virus (MMTV)-Wnt-1 and MMTV-c-Neu transgenic carcinomasHeregulin promotes expression and subcellular redistribution of ADP-ribosylation factor 3Up-regulation of vascular endothelial growth factor C in breast cancer cells by heregulin-beta 1. A critical role of p38/nuclear factor-kappa B signaling pathwayPak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptorBinding of activated alpha2-macroglobulin to its cell surface receptor GRP78 in 1-LN prostate cancer cells regulates PAK-2-dependent activation of LIMKThe Role of the Pleckstrin Homology Domain-containing Protein CKIP-1 in Activation of p21-activated Kinase 1 (PAK1)Molecular pathways: targeting p21-activated kinase 1 signaling in cancer--opportunities, challenges, and limitationsPhosphorylation of the ErbB3 binding protein Ebp1 by p21-activated kinase 1 in breast cancer cellsSRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migrationRegulation of phosphoglucomutase 1 phosphorylation and activity by a signaling kinaseErbB4 expression in neural progenitor cells (ST14A) is necessary to mediate neuregulin-1beta1-induced migrationInhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3Mitogen-activated protein kinase feedback phosphorylation regulates MEK1 complex formation and activation during cellular adhesion.Inhibition of the Rho GTPase, Rac1, decreases estrogen receptor levels and is a novel therapeutic strategy in breast cancer.The role of Shc and insulin-like growth factor 1 receptor in mediating the translocation of estrogen receptor alpha to the plasma membrane.PI3K and Erk MAPK mediate ErbB signaling in Xenopus gastrulation.PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics.Regulation of the Cool/Pix proteins: key binding partners of the Cdc42/Rac targets, the p21-activated kinases.Evidence of Rab3A expression, regulation of vesicle trafficking, and cellular secretion in response to heregulin in mammary epithelial cells.Fluorescence recovery after photobleaching and photoconversion in multiple arbitrary regions of interest using a programmable array microscope.Lysophosphatidic acid induces MDA-MB-231 breast cancer cells migration through activation of PI3K/PAK1/ERK signaling.
P2860
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P2860
Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Heregulin regulates cytoskelet ...... phosphatidylinositol-3 kinase
@ast
Heregulin regulates cytoskelet ...... phosphatidylinositol-3 kinase
@en
Heregulin regulates cytoskelet ...... phosphatidylinositol-3 kinase
@nl
type
label
Heregulin regulates cytoskelet ...... phosphatidylinositol-3 kinase
@ast
Heregulin regulates cytoskelet ...... phosphatidylinositol-3 kinase
@en
Heregulin regulates cytoskelet ...... phosphatidylinositol-3 kinase
@nl
prefLabel
Heregulin regulates cytoskelet ...... phosphatidylinositol-3 kinase
@ast
Heregulin regulates cytoskelet ...... phosphatidylinositol-3 kinase
@en
Heregulin regulates cytoskelet ...... phosphatidylinositol-3 kinase
@nl
P2093
P2860
P3181
P356
P1476
Heregulin regulates cytoskelet ...... phosphatidylinositol-3 kinase
@en
P2093
J Mendelsohn
R Vadlamudi
S B Kondapaka
P2860
P304
P3181
P356
10.1074/JBC.273.43.28238
P407
P577
1998-10-23T00:00:00Z