Mutation of a Shc binding site tyrosine residue in ErbB3/HER3 blocks heregulin-dependent activation of mitogen-activated protein kinase
about
Distinct domains of MuSK mediate its abilities to induce and to associate with postsynaptic specializationsRegulation of ERBB3/HER3 signaling in cancerHeregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 co-receptorNeuregulin-increased expression of acetylcholine receptor epsilon-subunit gene requires ErbB interaction with Shc.Screening for PTB domain binding partners and ligand specificity using proteome-derived NPXY peptide arrays.The C-terminus of the kinase-defective neuregulin receptor ErbB-3 confers mitogenic superiority and dictates endocytic routing.Nrdp1-mediated regulation of ErbB3 expression by the androgen receptor in androgen-dependent but not castrate-resistant prostate cancer cells.Kaempferol Downregulates Insulin-like Growth Factor-I Receptor and ErbB3 Signaling in HT-29 Human Colon Cancer Cells.The E3 ubiquitin ligase NEDD4 negatively regulates HER3/ErbB3 level and signaling.Profiling epidermal growth factor receptor and heregulin receptor 3 heteromerization using receptor tyrosine kinase heteromer investigation technology.PTEN Loss Is Associated with Worse Outcome in HER2-Amplified Breast Cancer Patients but Is Not Associated with Trastuzumab Resistance.Receptor tyrosine kinase signaling favors a protumorigenic state in breast cancer cells by inhibiting the adaptive immune response.The ERBB3 receptor in cancer and cancer gene therapyExploring Missense Mutations in Tyrosine Kinases Implicated with Neurodegeneration.Phosphorylation and nuclear exclusion of the forkhead transcription factor FKHR after epidermal growth factor treatment in human breast cancer cells.Advances in Targeting HER3 as an Anticancer TherapyTrans-10,cis-12, not cis-9,trans-11, conjugated linoleic acid decreases ErbB3 expression in HT-29 human colon cancer cells.Proteomic analysis of macrophage differentiation. p46/52(Shc) Tyrosine phosphorylation is required for CSF-1-mediated macrophage differentiation.Bimolecular complementation affinity purification (BiCAP) reveals dimer-specific protein interactions for ERBB2 dimers.The ShcA SH2 domain engages a 14-3-3/PI3'K signaling complex and promotes breast cancer cell survival.
P2860
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P2860
Mutation of a Shc binding site tyrosine residue in ErbB3/HER3 blocks heregulin-dependent activation of mitogen-activated protein kinase
description
1998 nî lūn-bûn
@nan
1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Mutation of a Shc binding site ...... togen-activated protein kinase
@ast
Mutation of a Shc binding site ...... togen-activated protein kinase
@en
Mutation of a Shc binding site ...... togen-activated protein kinase
@nl
type
label
Mutation of a Shc binding site ...... togen-activated protein kinase
@ast
Mutation of a Shc binding site ...... togen-activated protein kinase
@en
Mutation of a Shc binding site ...... togen-activated protein kinase
@nl
prefLabel
Mutation of a Shc binding site ...... togen-activated protein kinase
@ast
Mutation of a Shc binding site ...... togen-activated protein kinase
@en
Mutation of a Shc binding site ...... togen-activated protein kinase
@nl
P2093
P2860
P356
P1476
Mutation of a Shc binding site ...... togen-activated protein kinase
@en
P2093
P2860
P304
20996-1002
P356
10.1074/JBC.273.33.20996
P407
P577
1998-08-14T00:00:00Z