The human synMuv-like protein LIN-9 is required for transcription of G2/M genes and for entry into mitosis
about
LIN54 is an essential core subunit of the DREAM/LINC complex that binds to the cdc2 promoter in a sequence-specific mannerA B-Myb complex containing clathrin and filamin is required for mitotic spindle function.The association of mammalian DREAM complex and HPV16 E7 proteinsTranscriptional control of mitosis: deregulation and cancerA human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-αThe CHR site: definition and genome-wide identification of a cell cycle transcriptional elementLoss of the mammalian DREAM complex deregulates chondrocyte proliferationARF-induced downregulation of Mip130/LIN-9 protein levels mediates a positive feedback that leads to increased expression of p16Ink4a and p19Arf.The MuvB complex sequentially recruits B-Myb and FoxM1 to promote mitotic gene expression.Breed-dependent transcriptional regulation of 5'-untranslated GR (NR3C1) exon 1 mRNA variants in the liver of newborn piglets.The DREAM complex: master coordinator of cell cycle-dependent gene expression.B-Myb is critical for proper DNA duplication during an unperturbed S phase in mouse embryonic stem cellsInteraction of the transactivation domain of B-Myb with the TAZ2 domain of the coactivator p300: molecular features and properties of the complex.p53 and cell cycle dependent transcription of kinesin family member 23 (KIF23) is controlled via a CHR promoter element bound by DREAM and MMB complexes.LIN9, a subunit of the DREAM complex, regulates mitotic gene expression and proliferation of embryonic stem cells.DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly.Unique aspects of transcription regulation in male germ cellsMYBL2 is an independent prognostic marker that has tumor-promoting functions in colorectal cancer.The CHR promoter element controls cell cycle-dependent gene transcription and binds the DREAM and MMB complexes.The SynMuv genes of Caenorhabditis elegans in vulval development and beyondGenomic profiling and expression studies reveal both positive and negative activities for the Drosophila Myb MuvB/dREAM complex in proliferating cellsMip/LIN-9 can inhibit cell proliferation independent of the pocket proteins.E2F-associated chromatin modifiers and cell cycle controllin9 is required for mitosis and cell survival during early zebrafish development.Deletion of the p107/p130-binding domain of Mip130/LIN-9 bypasses the requirement for CDK4 activity for the dissociation of Mip130/LIN-9 from p107/p130-E2F4 complexLIN-9 phosphorylation on threonine-96 is required for transcriptional activation of LIN-9 target genes and promotes cell cycle progression.The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription.Human papillomavirus type 16 E7 perturbs DREAM to promote cellular proliferation and mitotic gene expression.Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex.LIN54 harboring a mutation in CHC domain is localized to the cytoplasm and inhibits cell cycle progression.Preferential up-regulation of G2/M phase-specific genes by overexpression of the hyperactive form of NtmybA2 lacking its negative regulation domain in tobacco BY-2 cells.In vitro and in vivo analysis of B-Myb in basal-like breast cancerMYBL2 (B-Myb): a central regulator of cell proliferation, cell survival and differentiation involved in tumorigenesis.Central spindle proteins and mitotic kinesins are direct transcriptional targets of MuvB, B-MYB and FOXM1 in breast cancer cell lines and are potential targets for therapyAn important role for Myb-MuvB and its target gene KIF23 in a mouse model of lung adenocarcinoma.Epigenetic gene regulation by histone demethylases: emerging role in oncogenesis and inflammation.A functional interaction of E7 with B-Myb-MuvB complex promotes acute cooperative transcriptional activation of both S- and M-phase genes. (129 c).Polo-like kinase 4 transcription is activated via CRE and NRF1 elements, repressed by DREAM through CDE/CHR sites and deregulated by HPV E7 protein.B-Myb promotes S-phase independently of its sequence-specific DNA binding activity and interacts with polymerase delta-interacting protein 1 (Pdip1)Loss of LIN9, a member of the DREAM complex, cooperates with SV40 large T antigen to induce genomic instability and anchorage-independent growth.
P2860
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P2860
The human synMuv-like protein LIN-9 is required for transcription of G2/M genes and for entry into mitosis
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The human synMuv-like protein ...... nes and for entry into mitosis
@ast
The human synMuv-like protein ...... nes and for entry into mitosis
@en
The human synMuv-like protein ...... nes and for entry into mitosis
@en-gb
The human synMuv-like protein ...... nes and for entry into mitosis
@nl
type
label
The human synMuv-like protein ...... nes and for entry into mitosis
@ast
The human synMuv-like protein ...... nes and for entry into mitosis
@en
The human synMuv-like protein ...... nes and for entry into mitosis
@en-gb
The human synMuv-like protein ...... nes and for entry into mitosis
@nl
prefLabel
The human synMuv-like protein ...... nes and for entry into mitosis
@ast
The human synMuv-like protein ...... nes and for entry into mitosis
@en
The human synMuv-like protein ...... nes and for entry into mitosis
@en-gb
The human synMuv-like protein ...... nes and for entry into mitosis
@nl
P2093
P2860
P356
P1433
P1476
The human synMuv-like protein ...... nes and for entry into mitosis
@en
P2093
Birgit Samans
Denise Hübner
Fabienne Schmit
Lisa Osterloh
Stefanie Hauser
P2860
P304
P356
10.1038/SJ.EMBOJ.7601478
P407
P577
2006-12-07T00:00:00Z