Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system
about
Translational repression precedes and is required for ZAP-mediated mRNA decayStructural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding proteinMammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylationThe Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferationmiRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decayKinetic signatures of microRNA modes of actionTrading translation with RNA-binding proteinsRibosomal protein RPS-14 modulates let-7 microRNA function in Caenorhabditis elegansDeadenylation is a widespread effect of miRNA regulationA functional MicroRNA-155 ortholog encoded by the oncogenic Marek's disease virusAn Emerging Role of micro-RNA in the Effect of the Endocrine DisruptorsDifferential expression of microRNAs in different disease states.Origins and Mechanisms of miRNAs and siRNAsRegulation of translation initiation in eukaryotes: mechanisms and biological targetseIF4GI facilitates the MicroRNA-mediated gene silencingPrecursor microRNA-programmed silencing complex assembly pathways in mammalsObesity resistance and increased hepatic expression of catabolism-related mRNAs in Cnot3+/- miceSlicer-independent mechanism drives small-RNA strand separation during human RISC assemblyCytoplasmic polyadenylation and cytoplasmic polyadenylation element-dependent mRNA regulation are involved in Xenopus retinal axon development.Concordant regulation of translation and mRNA abundance for hundreds of targets of a human microRNATarget-specific requirements for enhancers of decapping in miRNA-mediated gene silencing.Coexpression of Argonaute-2 enhances RNA interference toward perfect match binding sites.microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells.A probabilistic framework to improve microrna target prediction by incorporating proteomics data.Dynamical modeling of microRNA action on the protein translation process.Non-canonical targets destabilize microRNAs in human ArgonautesPoly(A)-binding protein modulates mRNA susceptibility to cap-dependent miRNA-mediated repression.miRNAs in human cancer.Sweating the small stuff: microRNAs and genetic changes define pancreatic cancer.Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps.The code within the code: microRNAs target coding regions.To polyadenylate or to deadenylate: that is the question.The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC.Phosphorylation of tristetraprolin by MK2 impairs AU-rich element mRNA decay by preventing deadenylase recruitment.MicroRNAs in Cancer Biology and Therapy: Current Status and Perspectives.Regulation of mRNA translation in renal physiology and disease.The complexity of miRNA-mediated repressionmRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues.mRNA isoform diversity can obscure detection of miRNA-mediated control of translation.Activation of a microRNA response in trans reveals a new role for poly(A) in translational repression
P2860
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P2860
Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Let-7 microRNA-mediated mRNA d ...... n a mammalian cell-free system
@ast
Let-7 microRNA-mediated mRNA d ...... n a mammalian cell-free system
@en
Let-7 microRNA-mediated mRNA d ...... n a mammalian cell-free system
@en-gb
Let-7 microRNA-mediated mRNA d ...... n a mammalian cell-free system
@nl
type
label
Let-7 microRNA-mediated mRNA d ...... n a mammalian cell-free system
@ast
Let-7 microRNA-mediated mRNA d ...... n a mammalian cell-free system
@en
Let-7 microRNA-mediated mRNA d ...... n a mammalian cell-free system
@en-gb
Let-7 microRNA-mediated mRNA d ...... n a mammalian cell-free system
@nl
prefLabel
Let-7 microRNA-mediated mRNA d ...... n a mammalian cell-free system
@ast
Let-7 microRNA-mediated mRNA d ...... n a mammalian cell-free system
@en
Let-7 microRNA-mediated mRNA d ...... n a mammalian cell-free system
@en-gb
Let-7 microRNA-mediated mRNA d ...... n a mammalian cell-free system
@nl
P2860
P921
P3181
P356
P1433
P1476
Let-7 microRNA-mediated mRNA d ...... n a mammalian cell-free system
@en
P2093
Koji Takimoto
Motoaki Wakiyama
P2860
P304
P3181
P356
10.1101/GAD.1566707
P407
P577
2007-08-01T00:00:00Z