The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway.
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The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cellsDomain-specific function of ShcC docking protein in neuroblastoma cellsShc3 affects human high-grade astrocytomas survivalRAI(ShcC/N-Shc)-dependent recruitment of GAB 1 to RET oncoproteins potentiates PI 3-K signalling in thyroid tumorsLinkage and association studies in African- and Caucasian-American populations demonstrate that SHC3 is a novel susceptibility locus for nicotine dependenceAnalysis of a Shc family adaptor protein, ShcD/Shc4, that associates with muscle-specific kinaseCellular heterogeneity during embryonic stem cell differentiation to epiblast stem cells is revealed by the ShcD/RaLP adaptor proteinElevated gene expression levels distinguish human from non-human primate brainsThe Intersection of NGF/TrkA Signaling and Amyloid Precursor Protein Processing in Alzheimer's Disease NeuropathologyThe Shc family protein adaptor, Rai, negatively regulates T cell antigen receptor signaling by inhibiting ZAP-70 recruitment and activation.Quantitative phosphoproteomic analysis identifies activation of the RET and IGF-1R/IR signaling pathways in neuroblastoma.Biological role of anaplastic lymphoma kinase in neuroblastoma.ShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation.Regulation of neural development by glial cell line-derived neurotrophic factor family ligands.NGF controls APP cleavage by downregulating APP phosphorylation at Thr668: relevance for Alzheimer's disease.The Rai (Shc C) adaptor protein regulates the neuronal stress response and protects against cerebral ischemia.The ShcD signaling adaptor facilitates ligand-independent phosphorylation of the EGF receptor.Can "functional" constipation be considered as a form of enteric neuro-gliopathy?The Hirschsprung's-multiple endocrine neoplasia connection.Teaching an old dogma new tricks: twenty years of Shc adaptor signalling.The RET oncogene in papillary thyroid carcinoma.Signaling adaptor ShcD suppresses extracellular signal-regulated kinase (Erk) phosphorylation distal to the Ret and Trk neurotrophic receptors.Deciphering adaptor specificity in GFL-dependent RET-mediated proliferation and neurite outgrowth.Cellular signaling pathway alterations and potential targeted therapies for medullary thyroid carcinoma.Insights into the Shc Family of Adaptor Proteins.The Shc protein RAI promotes an adaptive cell survival program in hypoxic neuroblastoma cells.The neuronal Shc adaptor in Alzheimer's Disease.The Adaptor Protein Rai/ShcC Promotes Astrocyte-Dependent Inflammation during Experimental Autoimmune Encephalomyelitis.Rai is a new regulator of neural progenitor migration and glioblastoma invasion.2x p-5Y-RET:GDNF:GFRA complexes bind RET interactorsManganese-Mediated Decrease in Levels of c-RET and Tyrosine Hydroxylase Expression In Vitro.The Shc family protein adaptor, Rai, acts as a negative regulator of Th17 and Th1 cell development.Different Effects of p52SHC1 and p52SHC3 on the Cell Cycle of Neurons and Neural Stem Cells.The role of the ShcD and RET interaction in neuroblastoma survival and migration.Cell density modulates SHC3 expression and survival of human glioblastoma cells through Fak activation.The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone DeacetylationMelanoma: targeting signaling pathways and RaLPExpression of the Rai (Shc C) adaptor protein in the human enteric nervous system
P2860
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P2860
The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway.
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2002 nî lūn-bûn
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2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
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2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
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2002年論文
@zh-mo
2002年論文
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2002年论文
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name
The neuron-specific Rai (ShcC) ...... 3-kinase/Akt signaling pathway
@nl
The neuron-specific Rai (ShcC) ...... -kinase/Akt signaling pathway.
@ast
The neuron-specific Rai (ShcC) ...... -kinase/Akt signaling pathway.
@en
type
label
The neuron-specific Rai (ShcC) ...... 3-kinase/Akt signaling pathway
@nl
The neuron-specific Rai (ShcC) ...... -kinase/Akt signaling pathway.
@ast
The neuron-specific Rai (ShcC) ...... -kinase/Akt signaling pathway.
@en
prefLabel
The neuron-specific Rai (ShcC) ...... 3-kinase/Akt signaling pathway
@nl
The neuron-specific Rai (ShcC) ...... -kinase/Akt signaling pathway.
@ast
The neuron-specific Rai (ShcC) ...... -kinase/Akt signaling pathway.
@en
P2093
P2860
P3181
P1476
The neuron-specific Rai (ShcC) ...... 3-kinase/Akt signaling pathway
@en
P2093
Alessandra Bodini
Antonio De Giuseppe
Flavia Troglio
Giuliana Pelicci
Laura Coda
Massimo Santoro
Pier Giuseppe Pelicci
Valentina Pettirossi
P2860
P304
P3181
P356
10.1128/MCB.22.20.7351-7363.2002
P407
P577
2002-10-01T00:00:00Z