Vac7p, a novel vacuolar protein, is required for normal vacuole inheritance and morphology - Wikidata - awgldk - TriplyDB

Vac7p, a novel vacuolar protein, is required for normal vacuole inheritance and morphology

Vac7p, a novel vacuolar protein, is required for normal vacuole inheritance and morphology

http://www.wikidata.org/entity/Q24644105

about

The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport.VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse.Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member.A mammalian ortholog of Saccharomyces cerevisiae Vac14 that associates with and up-regulates PIKfyve phosphoinositide 5-kinase activity TRAPP stably associates with the Golgi and is required for vesicle docking In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P.Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphatase The Vac14p-Fig4p complex acts independently of Vac7p and couples PI3,5P2 synthesis and turnover Phosphatidylinositol 3,5-bisphosphate: low abundance, high significance The Fab1/PIKfyve phosphoinositide phosphate kinase is not necessary to maintain the pH of lysosomes and of the yeast vacuole.Vac8p, a vacuolar protein with armadillo repeats, functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p.Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasis Genome-wide analysis of AP-3-dependent protein transport in yeast p21-activated kinases Cla4 and Ste20 regulate vacuole inheritance in Saccharomyces cerevisiae.Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase Identification of yeast deletion strains that are hypersensitive to brefeldin A or monensin, two drugs that affect intracellular transport.Regulated degradation of a class V myosin receptor directs movement of the yeast vacuole.Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors.Atg18 regulates organelle morphology and Fab1 kinase activity independent of its membrane recruitment by phosphatidylinositol 3,5-bisphosphate Ent5p is required with Ent3p and Vps27p for ubiquitin-dependent protein sorting into the multivesicular body.Vacuole biogenesis in Saccharomyces cerevisiae: protein transport pathways to the yeast vacuole Identification of an organelle-specific myosin V receptor.Assortment of phosphatidylinositol 3-kinase complexes--Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae.Nucleus-vacuole junctions in Saccharomyces cerevisiae are formed through the direct interaction of Vac8p with Nvj1p.Complementation analysis in PtdInsP kinase-deficient yeast mutants demonstrates that Schizosaccharomyces pombe and murine Fab1p homologues are phosphatidylinositol 3-phosphate 5-kinases Neuronal expression of Fig4 is both necessary and sufficient to prevent spongiform neurodegeneration.Non-repair pathways for minimizing protein isoaspartyl damage in the yeast Saccharomyces cerevisiae.Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae Discovery of mutations in Saccharomyces cerevisiae by pooled linkage analysis and whole-genome sequencing Phosphoinositide 5-phosphatase Fig 4p is required for both acute rise and subsequent fall in stress-induced phosphatidylinositol 3,5-bisphosphate levels.Activity-dependent PI(3,5)P2 synthesis controls AMPA receptor trafficking during synaptic depression.Identification of genes affecting vacuole membrane fragmentation in Saccharomyces cerevisiae The transient receptor potential channel on the yeast vacuole is mechanosensitive.Cell-free reconstitution of vacuole membrane fragmentation reveals regulation of vacuole size and number by TORC1.The vacuole/lysosome is required for cell-cycle progression.Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1.Modulation of synaptic function by VAC14, a protein that regulates the phosphoinositides PI(3,5)P₂ and PI(5)P Retrograde traffic out of the yeast vacuole to the TGN occurs via the prevacuolar/endosomal compartment.The vacuolar kinase Yck3 maintains organelle fragmentation by regulating the HOPS tethering complex.

P2860

3ba751b42e5014ba4f38d2292c4726d6080e3379 85dc52bf6a586a289d24d1c83c9dcf3065812632 d44090a5d7c4cc38bb32a4498459afd48d1df35d

P248

Q24301637-FC0CB6E4-79B7-4CEC-B930-543E3BE3F473 Q24318746-4988E4F5-4C67-47E3-8461-BDB77AEDC137 Q24515262-01722A28-23C6-48DA-8112-59EF965668FD Q24559992-99995AD4-13D6-4AC6-8FD8-CD1D95A59078 Q24600972-5E4580B0-DFD6-4A8A-B5F1-7E5F1F4EEE07 Q24617439-FC19CEF8-ACBD-4E0E-8D26-36394EDFA8C6 Q24643186-2B80FA1B-4ED6-481A-B5B2-5E16D4479791 Q24683845-98A1D6D3-FA68-40A8-BC47-39807F2CED7B Q26823539-1F0DEFA4-C220-4996-B687-0C1096288D04 Q27314340-E7FFD02B-7D33-4E86-AE84-474F6E690D4C Q27930646-5C016F16-E39B-4798-8971-DEF8D5F375B3 Q27930743-636C6CF5-CADD-4F66-8A21-449FD8B9F5BC Q27931112-7E30E82B-BECD-40C6-A3A3-DDDD3244DA08 Q27933024-ECB2B94C-A14F-40B5-8BF0-33F27BA76ADD Q27933228-9C9FF22C-1416-45DC-8706-FAAB91449241 Q27933521-5E6FAF43-4CC5-4C6D-A6B6-8250602F995B Q27934131-FEE4DB73-4882-4DB9-9466-02DF4510D56A Q27936360-A03F5F81-57E5-4D41-98F4-A2B836665A4F Q27936381-2C7FD990-4358-4002-B572-6C10CB92D456 Q27936744-1325128B-AFF6-4309-B232-AE2492472CC9 Q27937954-F41DE9F1-EEB3-4C65-8BB8-5A3319F188B1 Q27938062-ED222759-7E2B-4DD4-B67C-AFEC739807AE Q27939242-C98E2BDD-1CFD-43E0-9043-D70058034850 Q27940258-2B8DDAE3-2317-48D5-92A4-65B553C04A66 Q27940306-A0F988C9-A205-4915-8C3E-E60D8F5B825D Q28678528-B0BF0249-6795-480C-A95D-2DDAEB57EF48 Q30523191-E595846E-FE0B-4CA5-B180-F13151456FB1 Q33761245-3FFA84B9-3F35-4843-B85D-201CC0311330 Q33893822-A5FC9223-EBA2-4C43-807B-5617E3CA5DC1 Q34386830-3368D8B0-0BB8-4E94-8EAB-701B7B614443 Q34512579-9C40FF47-B0E0-449D-A0C0-109EB4C57E68 Q34526188-ECB3AC24-A1E2-4E8B-9346-73F9BC834259 Q34577025-7581A38F-DA0E-4CE9-948F-7487AA514302 Q35163125-DBE0DE75-6BA1-4878-A34C-BC09311DE5EE Q35790915-F348F646-318B-4562-8BA0-29B5D64D9EF7 Q36101933-74AE18E3-8993-489E-84E3-908DDB04DFBE Q36127992-BBB9BDC4-1CC7-478B-A2FB-4BB2019B216C Q36166728-731F77A1-0A57-4BB6-9595-F66A859B382B Q36288266-636B6861-5FBC-4826-906B-D881F84CD515 Q36321361-C396F824-7A1C-4F21-B29A-90459385C0C1

P2860

Vac7p, a novel vacuolar protein, is required for normal vacuole inheritance and morphology

http://www.wikidata.org/entity/Q24644105

description

1997 nî lūn-bûn

@nan

1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1997年の論文

@ja

1997年論文

@yue

1997年論文

@zh-hant

1997年論文

@zh-hk

1997年論文

@zh-mo

1997年論文

@zh-tw

1997年论文

@wuu

name

Vac7p, a novel vacuolar protei ...... ole inheritance and morphology

@ast

Vac7p, a novel vacuolar protei ...... ole inheritance and morphology

@en

Vac7p, a novel vacuolar protei ...... ole inheritance and morphology

@nl

type

label

Vac7p, a novel vacuolar protei ...... ole inheritance and morphology

@ast

Vac7p, a novel vacuolar protei ...... ole inheritance and morphology

@en

Vac7p, a novel vacuolar protei ...... ole inheritance and morphology

@nl

prefLabel

Vac7p, a novel vacuolar protei ...... ole inheritance and morphology

@ast

Vac7p, a novel vacuolar protei ...... ole inheritance and morphology

@en

Vac7p, a novel vacuolar protei ...... ole inheritance and morphology

@nl

P1433

Q24644105-5734C49A-DB70-46D3-BE71-0E64DAFF4A86

P1476

Q24644105-EEE1BE6F-16D3-4489-B3C4-9DF1DCC41D0B

P2093

Q24644105-482B3897-D806-4076-BB73-461B6A2B5D94

Q24644105-D415B3C8-0A7B-44B2-9265-E2119F70B588

Q24644105-DC013B7F-47EB-4466-A15D-806A3028785D

P2860

Q24644105-0048896C-EBA7-428A-A28F-AFB64561E81D

Q24644105-0264DC6B-4AD0-43E1-974A-0A339E409C42

Q24644105-09D21D11-769C-4EFC-83CA-F9C7B7A27665

Q24644105-125D89E9-007C-4159-B588-385AAF68B9B5

Q24644105-12F24F56-4B70-444B-A130-075E52BB1402

Q24644105-13CFFBAA-AF6A-4DD1-A758-5B6B825062AB

Q24644105-1466AA43-53D0-42B5-8466-1B242694E151

Q24644105-2FE80FE6-1C1E-43A9-AECE-592A5C6DE01C

Q24644105-32DF53EB-E882-41E1-82A4-EA186F4D4FBB

Q24644105-34A8834C-D1B8-4D8C-B206-5254362D0A98

P304

Q24644105-25944160-C63D-42A5-AC4B-BF332CDC67F4

P31

Q24644105-ED6F8656-4D1F-411D-8B38-77840FDD4D9C

P356

Q24644105-91F27941-69CF-4325-A5FC-770575675911

P407

Q24644105-BDED8ED2-E23A-41CD-9CAC-58CAA8C2976D

P433

Q24644105-77E81203-4807-4C62-ACC5-1E3E4EBE29D1

P478

Q24644105-BB2FC026-C563-4377-A153-0BB7606FB024

P577

Q24644105-608B886B-7225-45CD-9831-5157DC640592

P5875

Q24644105-C7E0D96D-529A-4447-9C1E-E61C8EAF5518

P698

Q24644105-56583814-C6E2-4CDE-A7A9-AF538FF9C60C

P932

Q24644105-B1D5A7BD-AF36-497E-BC8A-1B3C76DFF8A8

P356

P1433

Molecular and Cellular Biology

P1476

Vac7p, a novel vacuolar protei ...... ole inheritance and morphology

@en

P2093

C J Bonangelino

http://www.w3.org/2001/XMLSchema#string

L S Weisman

http://www.w3.org/2001/XMLSchema#string

N L Catlett

http://www.w3.org/2001/XMLSchema#string

P2860

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

Actin and myosin function in directed vacuole movement during cell division in Saccharomyces cerevisiae

FKBP12-rapamycin target TOR2 is a vacuolar protein with an associated phosphatidylinositol-4 kinase activity.

Mitochondrial DNA maintenance in yeast requires a protein containing a region related to the GTP-binding domain of dynamin.

Homotypic vacuole fusion requires Sec17p (yeast alpha-SNAP) and Sec18p (yeast NSF)

Multiple classes of yeast mutants are defective in vacuole partitioning yet target vacuole proteins correctly

Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutants.

P304

6847-58

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/MCB.17.12.6847

http://www.w3.org/2001/XMLSchema#string

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

17

http://www.w3.org/2001/XMLSchema#string

P577

1997-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

13856864

http://www.w3.org/2001/XMLSchema#string

P698

9372916

http://www.w3.org/2001/XMLSchema#string

P932

232541

http://www.w3.org/2001/XMLSchema#string