Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex - Wikidata - awgldk - TriplyDB

Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

http://www.wikidata.org/entity/Q24654714

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Tracheal development and the von Hippel-Lindau tumor suppressor homolog in Drosophila Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7 Ubiquitination of a novel deubiquitinating enzyme requires direct binding to von Hippel-Lindau tumor suppressor protein ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexes SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex Identification of novel VHL target genes and relationship to hypoxic response pathways Expression of the FAT10 gene is highly upregulated in hepatocellular carcinoma and other gastrointestinal and gynecological cancers Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase.A ubiquitin ligase complex assembles linear polyubiquitin chains E6AP ubiquitin ligase mediates ubiquitylation and degradation of hepatitis C virus core protein Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation Erythroid-specific 5-aminolevulinate synthase protein is stabilized by low oxygen and proteasomal inhibition Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery.The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2 Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein HECT and RING finger families of E3 ubiquitin ligases at a glance Unstable mutants in the peripheral endosomal membrane component ALS2 cause early-onset motor neuron disease Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins Identification of Ror2 as a hypoxia-inducible factor target in von Hippel-Lindau-associated renal cell carcinoma The VHL tumor suppressor: master regulator of HIF Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1alpha transcriptional activity Analysis of CUL-5 expression in breast epithelial cells, breast cancer cell lines, normal tissues and tumor tissues Sequence and structural analysis of BTB domain proteins Oxygen sensing in retinal health and disease RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis Suppression of APOBEC3-mediated restriction of HIV-1 by Vif Elongin from Saccharomyces cerevisiae.The conserved RING-H2 finger of ROC1 is required for ubiquitin ligation A dominant-negative UBC12 mutant sequesters NEDD8 and inhibits NEDD8 conjugation in vivo Loss of PTEN facilitates HIF-1-mediated gene expression Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins Carboxyl-terminal transactivation activity of hypoxia-inducible factor 1 alpha is governed by a von Hippel-Lindau protein-independent, hydroxylation-regulated association with p300/CBP.The novel WD-repeat protein Morg1 acts as a molecular scaffold for hypoxia-inducible factor prolyl hydroxylase 3 (PHD3)Role of transforming growth factor-alpha in von Hippel--Lindau (VHL)(-/-) clear cell renal carcinoma cell proliferation: a possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesis Vhlh gene deletion induces Hif-1-mediated cell death in thymocytes Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice.The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice CUL-4A is critical for early embryonic development Oxygen-dependent ubiquitination and degradation of hypoxia-inducible factor requires nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein

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Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

http://www.wikidata.org/entity/Q24654714

description

1999 nî lūn-bûn

@nan

1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի հոտեմբերին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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name

Identification of the von Hipp ...... ve E3 ubiquitin ligase complex

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Identification of the von Hipp ...... ve E3 ubiquitin ligase complex

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Identification of the von Hipp ...... ve E3 ubiquitin ligase complex

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Identification of the von Hipp ...... ve E3 ubiquitin ligase complex

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Identification of the von Hipp ...... ve E3 ubiquitin ligase complex

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Identification of the von Hipp ...... ve E3 ubiquitin ligase complex

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prefLabel

Identification of the von Hipp ...... ve E3 ubiquitin ligase complex

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Identification of the von Hipp ...... ve E3 ubiquitin ligase complex

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Identification of the von Hipp ...... ve E3 ubiquitin ligase complex

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Proceedings of the National Academy of Sciences of the United States of America

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Identification of the von Hipp ...... ve E3 ubiquitin ligase complex

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A Pause

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J W Conaway

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N Minato

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R C Conaway

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R D Klausner

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T Kamura

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P2860

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

A family of cytokine-inducible inhibitors of signalling

A new protein containing an SH2 domain that inhibits JAK kinases

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

Twenty proteins containing a C-terminal SOCS box form five structural classes

A new NEDD8-ligating system for cullin-4A

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

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