Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domain
about
Atomic force microscopy (AFM) imaging suggests that stromal interaction molecule 1 (STIM1) binds to Orai1 with sixfold symmetrySTIM and Orai1 Variants in Store-Operated Calcium EntryStructural aspects of calcium-release activated calcium channel functionOrai1 calcium channels in the vasculatureOrai3--the 'exceptional' Orai?The STIM1/Orai signaling machineryStore-operated Orai channels: structure and functionResting state Orai1 diffuses as homotetramer in the plasma membrane of live mammalian cellsTRPC3 regulates agonist-stimulated Ca2+ mobilization by mediating the interaction between type I inositol 1,4,5-trisphosphate receptor, RACK1, and Orai1Molecular basis of calcium signaling in lymphocytes: STIM and ORAIThe N-terminal domain of Orai3 determines selectivity for activation of the store-independent ARC channel by arachidonic acid.Graded activation of CRAC channel by binding of different numbers of STIM1 to Orai1 subunitsMutations in Orai1 transmembrane segment 1 cause STIM1-independent activation of Orai1 channels at glycine 98 and channel closure at arginine 91.STIM and Orai proteins and the non-capacitative ARC channels.How many Orai's does it take to make a CRAC channel?Redox regulation of endothelial canonical transient receptor potential channels.Ca(2+) release-activated Ca(2+) (CRAC) current, structure, and function.Exploring the unique features of the ARC channel, a store-independent Orai channel.Structural and functional mechanisms of CRAC channel regulation.Molecular mechanisms of STIM/Orai communication.Differential Redox Regulation of Ca²⁺ Signaling and Viability in Normal and Malignant Prostate Cells.ICRAC controls the rapid androgen response in human primary prostate epithelial cells and is altered in prostate cancer.Visualizing Quantum Dot Labeled ORAI1 Proteins in Intact Cells Via Correlative Light and Electron Microscopy.Visualization of the Orai1 homodimer and the functional coupling of Orai1-STIM1 by live-cell fluorescence lifetime imaging.The molecular architecture of the arachidonate-regulated Ca2+-selective ARC channel is a pentameric assembly of Orai1 and Orai3 subunits.Ca(2+) influx in T cells: how many ca(2+) channels?Optical control of membrane tethering and interorganellar communication at nanoscales.Regulation of endogenous and heterologous Ca²⁺ release-activated Ca²⁺ currents by pH.Is there competition in trafficking of VDAC-cored VRAC and SOC in NE differentiation of cells?The Orai1 Store-operated Calcium Channel Functions as a Hexamer.sp2 -Iminosugar α-glucosidase inhibitor 1-C-octyl-2-oxa-3-oxocastanospermine specifically affected breast cancer cell migration through Stim1, β1-integrin, and FAK signaling pathways.The store-operated calcium channels in cancer metastasis: from cell migration, invasion to metastatic colonization.The STIM-Orai Pathway: The Interactions Between STIM and Orai.The STIM-Orai Pathway: Orai, the Pore-Forming Subunit of the CRAC Channel.The STIM-Orai Pathway: STIM-Orai Structures: Isolated and in Complex.Store-Operated Calcium Channels.A Microscopic View of the Store-Operated Calcium Entry-Pathway
P2860
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P2860
Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domain
description
2009 nî lūn-bûn
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2009 թուականի Մարտին հրատարակուած գիտական յօդուած
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2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domain
@ast
Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domain
@en
type
label
Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domain
@ast
Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domain
@en
prefLabel
Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domain
@ast
Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domain
@en
P2093
P2860
P356
P1476
Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domain
@en
P2093
Kenta Kato
Shigeki Kiyonaka
Takeshi Kaneko
Toshihiko Ogura
Yasuo Mori
Yuusuke Maruyama
P2860
P304
13676-13685
P356
10.1074/JBC.M900812200
P407
P577
2009-03-16T00:00:00Z