Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2

Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2

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http://www.wikidata.org/entity/Q27652810
Structures of BIR domains from human NAIP and cIAP2Recognition of Smac-mimetic compounds by the BIR domain of cIAP1Structural Insight into Inhibitor of Apoptosis Proteins Recognition by a Potent Divalent Smac-MimeticEctopic expression of new alternative splice variant of Smac/DIABLO increases mammospheres formationHigh-throughput screening for modulators of protein-protein interactions: use of photonic crystal biosensors and complementary technologies.Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and BortezomibBV6, an IAP antagonist, activates apoptosis and enhances radiosensitization of non-small cell lung carcinoma in vitroPotential therapeutic benefits of strategies directed to mitochondria.HAX1 regulates E3 ubiquitin ligase activity of cIAPs by promoting their dimerization2P2I HUNTER: a tool for filtering orthosteric protein-protein interaction modulators via a dedicated support vector machine.Small molecules, big targets: drug discovery faces the protein-protein interaction challenge.Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling.Molecular determinants of Smac mimetic induced degradation of cIAP1 and cIAP2.Sensitization of human bladder tumor cells to TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis with a small molecule IAP antagonist.Loss of cellular inhibitor of apoptosis protein 2 reduces atherosclerosis in atherogenic apoE-/- C57BL/6 mice on high-fat diet.A NMR and computational study of Smac mimics targeting both the BIR2 and BIR3 domains in XIAP protein.
P2860

Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2

Item
http://www.wikidata.org/entity/Q27652810
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2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2
@ast
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2
@en
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2
@nl
type
label
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2
@ast
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2
@en
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2
@nl
prefLabel
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2
@ast
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2
@en
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2
@nl
P1433
P1476
P2093
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P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2
@en
P2093
P304
P31
P356
10.1016/J.BBRC.2008.10.139
P407
P433
P478
P50
P577
P698