MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae.
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The telomere syndromesTelomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae.Regulation of telomere structure and functions by subunits of the INO80 chromatin remodeling complex.Polymerase epsilon is required to maintain replicative senescence.Length-dependent processing of telomeres in the absence of telomerase.Recruitment of Rad51 and Rad52 to short telomeres triggers a Mec1-mediated hypersensitivity to double-stranded DNA breaks in senescent budding yeastTwo routes to senescence revealed by real-time analysis of telomerase-negative single lineages.The genome-wide transcription response to telomerase deficiency in the thermotolerant yeast Hansenula polymorpha DL-1.TOR regulates cell death induced by telomere dysfunction in budding yeast.Stabilization of dicentric translocations through secondary rearrangements mediated by multiple mechanisms in S. cerevisiae.A two-step model for senescence triggered by a single critically short telomere.An mre11 mutation that promotes telomere recombination and an efficient bypass of senescence.Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance.Phosphorylation of H2AX at short telomeres in T cells and fibroblasts.Telomerase RNA levels limit the telomere length equilibrium.Activation of a LTR-retrotransposon by telomere erosionShort telomeres induce a DNA damage response in Saccharomyces cerevisiae.Phenotypes in mTERT⁺/⁻ and mTERT⁻/⁻ mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptaseRad59-facilitated acquisition of Y' elements by short telomeres delays the onset of senescence.DNA breaks are masked by multiple Rap1 binding in yeast: implications for telomere capping and telomerase regulation.Reversibility of replicative senescence in Saccharomyces cerevisiae: effect of homologous recombination and cell cycle checkpoints.Host factors that control long terminal repeat retrotransposons in Saccharomyces cerevisiae: implications for regulation of mammalian retrovirusesMec1p associates with functionally compromised telomeresGenetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisae.Telomeres: the beginnings and ends of eukaryotic chromosomes.Regulation of Telomere Length Requires a Conserved N-Terminal Domain of Rif2 in Saccharomyces cerevisiae.Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end.ELG1, a regulator of genome stability, has a role in telomere length regulation and in silencing.Mdt1 facilitates efficient repair of blocked DNA double-strand breaks and recombinational maintenance of telomeres.Telomere cap components influence the rate of senescence in telomerase-deficient yeast cells.Factors influencing the recombinational expansion and spread of telomeric tandem arrays in Kluyveromyces lactis.Saccharomyces cerevisiae as a Model to Study Replicative Senescence Triggered by Telomere Shortening.ATM-like kinases and regulation of telomerase: lessons from yeast and mammalsAbnormal micronuclear telomeres lead to an unusual cell cycle checkpoint and defects in Tetrahymena oral morphogenesisRap1 relocalization contributes to the chromatin-mediated gene expression profile and pace of cell senescenceEnd resection initiates genomic instability in the absence of telomerase.The length of the shortest telomere as the major determinant of the onset of replicative senescenceShort telomeres are sufficient to cause the degenerative defects associated with agingTaming the tiger by the tail: modulation of DNA damage responses by telomeres.Ty1 mobilizes subtelomeric Y' elements in telomerase-negative Saccharomyces cerevisiae survivors.
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MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae.
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2002 nî lūn-bûn
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2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2002 թվականի օգոստոսին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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name
MEC3, MEC1, and DDC2 are essen ...... e in Saccharomyces cerevisiae.
@ast
MEC3, MEC1, and DDC2 are essen ...... e in Saccharomyces cerevisiae.
@en
MEC3, MEC1, and DDC2 are essen ...... e in Saccharomyces cerevisiae.
@nl
type
label
MEC3, MEC1, and DDC2 are essen ...... e in Saccharomyces cerevisiae.
@ast
MEC3, MEC1, and DDC2 are essen ...... e in Saccharomyces cerevisiae.
@en
MEC3, MEC1, and DDC2 are essen ...... e in Saccharomyces cerevisiae.
@nl
prefLabel
MEC3, MEC1, and DDC2 are essen ...... e in Saccharomyces cerevisiae.
@ast
MEC3, MEC1, and DDC2 are essen ...... e in Saccharomyces cerevisiae.
@en
MEC3, MEC1, and DDC2 are essen ...... e in Saccharomyces cerevisiae.
@nl
P2860
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P1476
MEC3, MEC1, and DDC2 are essen ...... e in Saccharomyces cerevisiae.
@en
P2093
Lynn Glowczewski
Shinichiro Enomoto
P2860
P304
P356
10.1091/MBC.02-02-0012
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P577
2002-08-01T00:00:00Z